Study of Olatorepatide for Overweight or Obesity

This study is testing a drug called Olatorepatide to see how safe and effective it is for adults who are overweight or have obesity. Researchers will also learn how your body handles the drug. You might receive Olatorepatide or a placebo (an inactive substance) in this study. We are looking for about 120 participants between 18 and 65 years old who have a Body Mass Index (BMI) between 27.0 and 45.0 kg/m². You cannot have a history of Type 1 or Type 2 diabetes. The main goals are to track any side effects, measure how much Olatorepatide is in your blood, and see how well it works. The study status is currently unclear.

Study design
This interventional study plans to enroll 120 participants. It compares Olatorepatide to a placebo.
What's involved
You will need to attend all scheduled visits and follow the prescribed treatment regimen. The study will measure side effects and drug levels in your blood.
Compensation
Not stated in the trial record.
Follow-up
Side effects will be measured for up to approximately 30 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07431086

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US

Active, Not Recruiting
PHASE2Ages 18–65InterventionalTreatment
Regeneron Pharmaceuticals
~120 participants
Updated 2026-06-17 on ClinicalTrials.gov
What's tested:OlatorepatidePlacebo

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Occurrence of Treatment-Emergent Adverse Events (TEAEs)
Measured over Up to approximately 30 weeks
+3 more outcomes measured
Overweight or Obesity
3 sites across 3 states
California1
Florida1
Texas1
  • Clinical Trial Management · STUDY_DIRECTOR · Regeneron Pharmaceuticals

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Occurrence of Treatment-Emergent Adverse Events (TEAEs)Up to approximately 30 weeks
  • Severity of TEAEsUp to approximately 30 weeks
  • Maximum plasma Concentration (Cmax)At week 15 and week 24
  • Area Under the Concentration time curve from time 0 to 168 hours (AUC0-168h)At week 15 and week 24