Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe Proteinuria

This study is looking at how to improve the referral process for adults who have signs of kidney disease, specifically blood (hematuria) and protein (proteinuria) in their urine. Researchers are testing if an alert in the electronic health record (EHR) system helps primary care providers (PCPs) refer patients to a kidney specialist (Nephrology) more often. The EHR alert will show important information about your urine test results and past visits to kidney or urology doctors. The main goal is to see if this alert leads to more referrals to Nephrology within one month of your PCP visit. You could be eligible if you are an adult receiving care from a Geisinger PCP and have these specific urine test results.

Study design: This is an interventional study planning to enroll 1200 participants. Patients will be randomly assigned to either receive care where their doctor gets an EHR alert or to receive usual care.
What's involved: Not specified in the trial record.
Compensation: Not stated in the trial record.
Follow-up: The study will look at referrals to Nephrology within one month, and also at 3 and 6 months after your initial PCP visit.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe Proteinuria

Not Yet Recruiting

NAAges 18+InterventionalScreening

Geisinger Clinic

~1,200 participants

Updated 2026-05-12 on ClinicalTrials.gov

What's tested:Electronic Health Record alert

At a glance

Recruiting sites

0 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Referral to Nephrology

Measured over Within One month of index PCP visit

Conditions

Referral and Consultation

Glomerulonephritis

Hematuria

Proteinuria

Kidney Disease

Where it's being run

1 sites across 1 states

Pennsylvania1

Who to contact

Alexander Chang, MD

[email protected]

570-214-3156

Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults aged ≥18 years

Patients receiving care from any Geisinger primary care provider (record of an encounter with a Geisinger PCP within the last 2 years from date of survey implementation)

Patients with high-risk glomerulonephritis features i.e. positive test results for hematuria (urine dipstick result with blood 1+ or greater) and proteinuria (2+ or 3+ protein on dipstick or ACR≥300 mg/g or PCR ≥500 mg/g) collected within 12 months of index date.

Exclusion

Patients with a nephrologist appointment in the last 12 months before the index date

Patients with a prior appointment with a nephrologist within the last 2 years before the positive urinalysis test for hematuria (1+ or greater)

Patients with a history of glomerulonephritis and/or kidney failure (dialysis or eGFR \< 15 mL/min/1.73m2, or kidney transplantation) at any time during the baseline

Patients receiving palliative care at any time during the baseline

What this trial measures

Referral to NephrologyWithin One month of index PCP visit
Proportion of adult patients with high-risk features for glomerulonephritis with a nephrology referral order

Trialytics