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Emergency Room Protocols for Treating Hyperthermia

This study is looking at how well different emergency room cooling methods work for people with hyperthermia (dangerously high body temperature). Researchers want to find out which methods are most effective. The cooling methods being tested include applying cooling packs, wrapping people in ice sheets with a fan, placing people in a body bag full of ice, and submerging them in cold water. To join, you need to be an active, healthy individual between 18 and 65 years old. You cannot be pregnant, have a pacemaker, or be taking medications that affect body temperature. The main goal is to measure how quickly your body temperature cools down with each method. The study is currently unclear on its recruitment status and plans to enroll 50 participants.

Study design
This is an interventional study, meaning participants will receive specific treatments. It plans to enroll 50 participants.
What's involved
You would have one preliminary session lasting about 1 hour, and five experimental sessions, each lasting about 3 hours. The total time commitment is approximately 16 hours.
Compensation
Not stated in the trial record.
Follow-up
The primary measurement of cooling rate occurs immediately after the exercise protocol, which can be 3 to 40 minutes post-exercise.

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NCT07433036

The Effectiveness of Emergency Room Protocols for Treating Hyperthermia

Recruiting
NAAges 18–65InterventionalTreatment
University of Colorado, Colorado Springs
~50 participants
Updated 2026-02-25 on ClinicalTrials.gov
What's tested:Passive coolingCooling packsIce sheetsBody bag coolingCold water immersion

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rectal temperature cooling rate
Measured over The measurement occurs immediately upon completion of the exercise protocol. Time itself is part of the outcome variable and will vary between participants (~3 to 40 min post exercise protocol).

Conditions

Hyperthermia

Explore related trials

Hyperthermia

Where it's being run

1 sites across 1 states
Colorado1

Who to contact

Nathan Morris, PhD
[email protected]
719-255-4466
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Active, healthy individuals

Exclusion

Pregnant or planning on becoming pregnant
Have a pacemaker
Currently taking any prescribed or over the counter medications or nutritional supplements known to influence thermoregulatory responses
Experience lingering pain from a previous musculoskeletal injury (i.e. knee, hip, or back pain)
Use tobacco/nicotine products

What this trial measures

  • Rectal temperature cooling rateThe measurement occurs immediately upon completion of the exercise protocol. Time itself is part of the outcome variable and will vary between participants (~3 to 40 min post exercise protocol).

    Following termination of the exercise protocol, at a core temperature above 39 degrees Celcius, participants will be cooled until they reach a core temperature of 38 degrees Celcius. The cooling rate in degrees Celcius per minute, is the primary outcome.