This study aims to help doctors understand the best amount of sterile 0.9% sodium chloride (saltwater solution) to use when cleaning open fracture wounds during surgery. You may be able to join if you are 18 or older and have an open fracture (a broken bone with a skin wound) in your arms or legs. Researchers will compare two different amounts of saltwater solution to see if one leads to better healing and fewer surgical site infections (infections at the surgery site). The main goal is to see if using less saltwater solution is just as good as using more to prevent infections. You would be in the study for about 12 months, and your recovery will be checked during your regular follow-up visits with your surgeon. Some later visits can even be done by phone, email, or mail.

Study design

This is a cluster randomized trial with 200 planned participants, comparing two different irrigation protocols. The study alternates between the two protocols every two months.

What's involved

You will be in the study for about 12 months, with your recovery checked during typical follow-up clinic visits. Later visits may be conducted by phone, email, or mail.

Compensation

Not stated in the trial record.

Follow-up

Your surgical site infection will be measured at 90 days after your first irrigation and debridement procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.