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Older Age and Generalization Study

This study aims to understand how memory works in healthy young and older adults, specifically focusing on how older adults make memory decisions by connecting different experiences. You could participate if you are a healthy adult aged 18-30 or 65-80, fluent in English, right-handed, and have normal vision. Participants will complete a memory task while having their brain activity measured using functional MRI (fMRI). Researchers will compare brain responses between young and older adults to see if memory integration changes with age. The study plans to enroll 360 people, but its current status is unclear.

Study design
This is an interventional study planning to enroll 360 participants, comparing memory responses in young and older adults.
What's involved
You will complete a memory task during one experimental session (Session 2) while undergoing functional MRI.
Compensation
Not stated in the trial record.
Follow-up
Your memory responses will be measured during Session 2, which is the experimental session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07440017

Older Age and Generalization

Recruiting
NAAges 18–80InterventionalBasic science
Caitlin Bowman
~360 participants
Updated 2026-06-17 on ClinicalTrials.gov
What's tested:Memory decision type

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Behavioral memory responses
Measured over Session 2 (experimental session)
+1 more outcome measured

Conditions

Aging

Explore related trials

Healthy Volunteers

NCT07440017

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Wisconsin-Milwaukee

    Milwaukee, Wisconsinstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Caitlin Bowman, PhD
[email protected]
414-251-5010
Email the study team

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Eligibility criteria

Inclusion

Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report)
Fluent in English (self-report)
Right-handed (self-report)
Cognitively healthy (self report verified by score \> 24 on Montreal Cognitive Assessment)
Self-reported normal or corrected-to-normal vision

Exclusion

Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease)
Self-reported uncontrolled hypertension, diabetes, or thyroid disorder
Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form)
Self-reported difficulty lying still on one's back for 1-2 hours

What this trial measures

  • Behavioral memory responsesSession 2 (experimental session)

    Participants will complete the study and test phases of a memory-based inference task designed by the investigators. The investigators will focus on the accuracy of decisions (0-100% scale with higher scores meaning better memory) and how long it takes to make correct decisions (in seconds, faster responses mean less cognitive processing needed).

  • Neural memory responsesSession 2 (experimental session)

    Investigators will measure the neural underpinnings of direct memory and the ability to make inferences.