Shatavari Root Extract for Perimenopausal Symptoms

This study is looking at whether a standardized Shatavari (Asparagus racemosus) root extract can help women with perimenopausal symptoms. Perimenopause is the time leading up to menopause, often causing irregular periods, hot flashes, and mood changes. Researchers want to see if taking one capsule of Shatavari root extract daily for 12 weeks improves symptoms compared to a placebo (an inactive capsule that looks the same). You might be able to join if you are a woman between 40 and 45 years old, have an intact uterus and ovaries, and have experienced irregular menstrual cycles or missed periods in the past year. The main way they will measure success is by looking at changes in your Menopause Rating Scale (MRS) score over 12 weeks. The study is currently recruiting 60 participants.

Study design
This is a randomized, double-blind, placebo-controlled study, meaning participants will be randomly assigned to receive either Shatavari root extract or a placebo, and neither you nor the researchers will know which you are receiving. It plans to enroll 60 participants.
What's involved
You would take one capsule daily for 12 weeks. Your Menopause Rating Scale (MRS) score will be measured at the beginning, and at weeks 4, 8, and 12.
Compensation
Not stated in the trial record.
Follow-up
Your symptoms will be assessed for 12 weeks after starting the intervention.

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NCT07441109

Shatavari Root Extract for Perimenopausal Symptoms

Not Yet Recruiting
NAAges 40–45InterventionalTreatment
SF Research Institute, Inc.
~60 participants
Updated 2026-03-03 on ClinicalTrials.gov
What's tested:Shatavari (Asparagus racemosus) Root ExtractPlacebo Capsule

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Menopause Rating Scale (MRS) Total Score
Measured over Baseline, Week 4, Week 8, Week 12
Perimenopause
Women Health
1 sites across 1 states
California1

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  • Change in Menopause Rating Scale (MRS) Total ScoreBaseline, Week 4, Week 8, Week 12

    The Menopause Rating Scale (MRS) is a validated 11-item questionnaire assessing the severity of menopausal symptoms across three domains: psychological, somato-vegetative, and urogenital. Each item is scored from 0 (no symptoms) to 4 (very severe symptoms). The total score ranges from 0 to 44, with higher scores indicating more severe menopausal symptoms (worse outcome). This outcome measures the mean change from baseline in MRS total score, where a reduction in score indicates improvement in overall perimenopausal symptom burden.