Simeox 200 for Bronchiectasis and Mucus Plug

This study is looking at how well a device called Simeox 200 helps adults with bronchiectasis (a lung condition where airways are widened and scarred) and too much mucus. The Simeox 200 device uses gentle air pressure to help move mucus out of the lungs. Researchers want to see how much wet sputum (mucus) you produce when using the device. They will also check your lung function, breathing symptoms, and how your health-related quality of life changes. To join, you need to be between 18 and 85 years old, have a confirmed diagnosis of bronchiectasis, a persistent cough, and produce at least 1 teaspoon of sputum daily. This study is currently unclear on its recruitment status.

Study design
This is a single-arm study, meaning all participants will receive the Simeox 200 device. It plans to include 35 adult participants.
What's involved
You would use the Simeox 200 device for two treatment sessions daily for two weeks. The study will measure your wet sputum during training and after each session on the training day.
Compensation
Not stated in the trial record.
Follow-up
Sputum weight is measured during training and up to one hour after each treatment session on the training day. Other follow-up details are not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07443124

Simeox 200 US Study

Not Yet Recruiting
NAAges 18–85InterventionalTreatment
Inogen Inc.
~35 participants
Updated 2026-03-02 on ClinicalTrials.gov
What's tested:Intermittent intrapulmonary deflation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Wet sputum weight collected with Simeox 200 during device training visit
Measured over From the first training session to the last, and up to one hour following each treatment session the day of training device visit.
Bronchiectasis
Mucus; Plug
1 sites across 1 states
South Carolina1
  • Patrick A Flume, MD · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

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  • Wet sputum weight collected with Simeox 200 during device training visitFrom the first training session to the last, and up to one hour following each treatment session the day of training device visit.

    Patients will be instructed during device training visit (V1) to spill all sputum into a pre-weighed pot from at least two supervised sessions. Immediately after collection, all sputum will be weighed on weighing scales with an accuracy of 0.01 grams.