This study aims to understand how the brain works in people with essential tremor, a movement disorder causing shaking, and how it changes after treatment with High-Intensity Focused Ultrasound (HiFU). HiFU uses focused sound waves to target a small brain area involved in tremor. Researchers will use safe, non-invasive tests like brain imaging (MRI and fMRI scans), brain wave recordings (MEG), and movement assessments to see how this treatment affects brain networks. You may be able to join if you are 50 to 84 years old, have essential tremor that hasn't responded to at least two medications, and meet certain skull density requirements. The main goal is to measure changes in brain electrical activity using MEG before and up to 7 months after HiFU treatment. The study plans to enroll 10 participants, and its current status is unclear.

Study design

This is an interventional study planning to enroll 10 participants. It is designed to observe changes in brain activity after treatment with High-Intensity Focused Ultrasound (HiFU).

What's involved

Participation will last about eight months, with a total of six study visits. These include a screening visit, an assessment before treatment, treatment visits, and follow-up assessments after treatment.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for changes in brain electrical activity for up to 7 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.