Sensory Substitution for Vision Loss
This study is exploring how the brain adapts when visual information is turned into patterns of sound or touch. Researchers are using two devices: the BrainPort, which translates video into gentle electrical pulses on the tongue, and AI Sight, which converts visual information into sound patterns you hear through headphones. Some participants will also use a sham device, which looks like the others but doesn't provide active signals. The study aims to see if these devices can improve visual performance in people who are blind or blindfolded, and how the brain changes in response. You may be able to join if you are 8 to 85 years old and blind, or 18 to 85 years old with normal vision. The study will measure how many correct responses you give on visual tasks, how quickly you respond, and your brain's metabolic profile after 5 weeks.
- Study design
- This is an interventional study planning to enroll 200 participants. It will compare how individuals with and without long-term vision loss respond to these signals.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be assessed at 5 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Sensory Substitution and Brain Plasticity Following Vision Loss
At a glance
Conditions
NCT07450677
Where you'd take part
This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Byers Eye Institute at Stanford University
Palo Alto, Californiastudy coordinator listed
LUCAS Center for Imaging
Stanford, Californiastudy coordinator listed
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Kevin C. Chan, PhD · PRINCIPAL_INVESTIGATOR · Stanford University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of correct responses to visual performance tasks5 weeks
Measuring the change in the number of correct responses to visual performance tasks from baseline to week 5.
- Reaction time to visual performance tasks5 weeks
Measuring the change in reaction time to visual performance tasks from baseline to week 5.
- Metabolic brain profile5 weeks
Measuring the change in neurometabolic markers by magnetic resonance spectroscopy from baseline to week 5.
- Blood-oxygenation-level-dependent functional brain activity level5 weeks
Measuring the change in blood-oxygenation-level-dependent brain activity level by T2\*-weighted functional magnetic resonance imaging from baseline to week 5.