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NCT07455370

A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses

Enrolling by Invitation
Not specifiedAll AgesObservational
Mayo Clinic
~21,300 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:Surveys

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Measure of Moral Distress-Healthcare Professionals (MMD-HP) Score
Measured over Baseline
+2 more outcomes measured

Conditions

Moral Injury
Moral Distress
Post-Traumatic Stress
Nurse Well-being
Wellbeing
Wellness, Psychological
Wellness
Nurses
Nurse Health

Explore related trials

Moral DistressMoral InjuryPosttraumatic state

Where it's being run

3 sites across 3 states
Arizona1
Florida1
Minnesota1

Study leadership

  • Melissa A Wilson, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic
  • Cindy Tofthagen, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Registered nurses
Licensed practical nurses
Nursing support staff (including roles such as patient care assistants, patient care specialists, medical assistants, and nurse technicians)

Exclusion

Social workers
Chaplains
Unit coordinators
Other staff who do not support direct patient care but are within the nursing department
Other employees outside the Department of Nursing

What this trial measures

  • Measure of Moral Distress-Healthcare Professionals (MMD-HP) ScoreBaseline

    The MMD-HP (Measure of Moral Distress-Healthcare Professionals) is a 27-item moral distress scale. A composite score is computed for items 1 - 25 and is obtained by multiplying the frequency scores (0 = Never to 4 = Very Frequently scale) and the distress scores (0 = None to 4 = Very Distressing scale) for each item; the products of these can range from 0 - 16. Higher scores indicate a greater deal of moral distress.

  • Moral Injury Outcome Scale (MIOS) scoreBaseline

    The Moral Injury Outcome Scale (MIOS) is a 14-item self-reported survey divided into two subscales-shame-related and trust-violation related. Both the shame and trust-violated subscales are seven items per subscale. Respondents are asked to indicate how strongly they agree with each statement in the past month using a 5 point Likert scale where 0 = Strongly Disagree and 4 = Strongly Agree. The total score range for each subscale is 0 - 28, and the overall score range is 0 - 56. Symptom severity is categorized as follows: 14 - 28 indicates mild moral injury, 29 - 42 indicates moderate moral injury, and 35 - 56 indicates severe moral injury.

  • Post-Traumatic Stress Disorder (PCL-5) scoreBaseline

    The PCL - 5 (Post-Traumatic Stress Disorder (PSTD) Checklist) is a 20-item self-reported survey that assesses the 20 DSM-5 symptoms of PTSD. Respondents are asked to indicate the frequency that each item occurs on a 5 point Likert scale where 0 = Not at All and 4 = Extremely. The total score is the sum of all 20 questions, with higher scores indicating a greater likelihood of PTSD.