Long-Term Study of ML-007C-MA for Schizophrenia

This study is looking at the long-term safety and how well a drug called ML-007C-MA works for adults with schizophrenia. You might be able to join if you are between 18 and 65 years old and have a diagnosis of schizophrenia. The main goal is to see if ML-007C-MA is safe and tolerable over a long period, up to 52 weeks. This study is open to people who have recently been in a related study (ML-007C-MA-211) or those who are new to this treatment. The study aims to enroll about 500 participants, but its current recruitment status is unclear.

Study design
This is an open-label study, meaning both you and your doctors will know you are receiving ML-007C-MA. It aims to enroll about 500 participants.
What's involved
You would take ML-007C-MA twice a day for up to 52 weeks, starting from your first dose until the end of treatment.
Compensation
Not stated in the trial record.
Follow-up
The study assesses safety and tolerability from the initial dose through the end of treatment, which can be up to 52 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07459647

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

Recruiting
PHASE2Ages 18–65InterventionalTreatment
MapLight Therapeutics
~500 participants
Updated 2026-08-13 on ClinicalTrials.gov
What's tested:ML-007C-MA

At a glance

Recruiting sites
41 of 41 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To assess the safety and tolerability of long-term ML-007C-MA administration in adult participants with schizophrenia
Measured over From initial dose through end of treatment (up to 52 weeks)
Schizophrenia
41 sites across 14 states
California15
Florida5
Arkansas3
New York3
Texas3
Georgia2
Massachusetts2
Ohio2
  • MapLight Therapeutics · STUDY_DIRECTOR · MapLight Therapeutics

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  • To assess the safety and tolerability of long-term ML-007C-MA administration in adult participants with schizophreniaFrom initial dose through end of treatment (up to 52 weeks)

    using the incidence of TEAEs, TE-SAEs, and TEAEs leading to study discontinuation.