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Virtual Reality E-cigarette Prevention for Adolescents

This study is testing a virtual reality (VR) program called "E-Invite Only VR" to help prevent e-cigarette use (vaping) and teach emotion regulation skills to middle school students. The program is an updated version of a VR game that includes mental health content alongside e-cigarette prevention education. The study aims to see if this program can reduce the number of students who start using e-cigarettes. You might be able to join if you are an 8th-grade student between 11 and 15 years old, enrolled in one of the partner middle schools in Connecticut or Massachusetts, and willing to play the VR game. The study will track whether participants start using e-cigarettes over 3, 6, and 12 months.

Study design
This interventional study plans to include 1251 participants. It is designed to evaluate a school-based virtual reality program.
What's involved
You would participate in a VR videogame for about 45 minutes per session, totaling 2-2.5 hours of gameplay across multiple class periods. You would also need to provide your agreement and get permission from a parent or guardian.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after the intervention to measure e-cigarette initiation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07460622

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

Not Yet Recruiting
NAAges 11–15InterventionalPrevention
Yale University
~1,251 participants
Updated 2026-03-10 on ClinicalTrials.gov
What's tested:Virtual Reality E-Cigarette Prevention Program

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants E-cigarette Initiation
Measured over 3, 6, and 12 months

Conditions

E-cigarette Use/Vaping Prevention
Nicotine Dependence Prevention
Adolescent Mental Health

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Nicotine Dependence

Where it's being run

1 sites across 1 states
Connecticut1

Study leadership

  • Kimberly Hieftje D Associate Professor of Pediatrics, PhD · PRINCIPAL_INVESTIGATOR · Yale University
  • Deepa Camenga Associate Professor of Emergency Medicine, MD · PRINCIPAL_INVESTIGATOR · Yale University

Who to contact

Kimberly Hieftje D Associate Professor of Pediatrics, PhD
[email protected]
12037375595
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Enrolled in the 8th grade in one of the 20 partner middle schools (8 in Connecticut, 12 in Massachusetts).
Willing to participate in a VR videogame for approximately 45 minutes per session, accumulating 2-2.5 hours of total gameplay across multiple class periods.
Able to provide assent and obtain parental/guardian consent before participating in the study.

Exclusion

Students not enrolled in 8th grade at one of the participating schools.
Students who are unwilling or unable to participate in VR gameplay for the required duration.
Students who cannot provide assent or do not have parental/guardian consent to participate .

What this trial measures

  • Number of participants E-cigarette Initiation3, 6, and 12 months

    E-cigarette use is defined as answering "yes" to the question: "Have you ever used an e-cigarette, even once or twice?" Participants will be classified as having initiated e-cigarette use if they report any past use at any of these time points.