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NCT07461584

Memory Enhancement in Aging With Optimal Dosing

Recruiting
NAAges 65+InterventionalBasic science
Boston University Charles River Campus
~240 participants
Updated 2026-07-22 on ClinicalTrials.gov
What's tested:1-day patterned tACS3-day patterned tACS5-day patterned tACS1-day continuous tACS3-day continuous tACS5-day continuous tACS

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual working memory capacity measured behaviorally
Measured over Baseline, 1-week after intervention, 1-month after intervention
+3 more outcomes measured

Conditions

Aging
Noninvasive Brain Stimulation
Memory

Explore related trials

Aging

Where it's being run

1 sites across 1 states
Massachusetts1

Study leadership

  • Robert Reinhart, PhD · PRINCIPAL_INVESTIGATOR · Boston University Charles River Campus

Who to contact

Robert Reinhart, PhD
[email protected]
(617) 353-9481
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Eligibility criteria

Inclusion

65 years of age or older
normal or corrected-to-normal vision
color vision

Exclusion

pregnant
metal implants in head
implanted electronic devices
history of neurological problems or head injury
skin sensitivity
claustrophobia
dementia (normal Montreal Cognitive Assessment \> 25)
depression (normal Geriatric Depression Scale \< 10)
history of psychosis
cognitive deficits (MoCA\>25)
any psychoactive medication

What this trial measures

  • Visual working memory capacity measured behaviorallyBaseline, 1-week after intervention, 1-month after intervention

    Behavioral k-capacity estimate derived from the change-detection task

  • Interruption suppression measured behaviorallyBaseline, 1-week after intervention, 1-month after intervention

    Memory accuracy performance difference between interruption and control trials on the interruption working memory task

  • EEG phase locking value (PLV) during working memory retentionBaseline, 1-week after intervention, 1-month after intervention

    Phase locking value between frontotemporal EEG electrodes within the theta frequency band during the memory retention interval of the visual working memory task

  • EEG phase amplitude coupling (PAC) during working memory retentionBaseline, 1-week after intervention, 1-month after intervention

    Theta phase gamma amplitude cross-frequency coupling at temporal EEG electrodes during the memory retention interval of the visual working memory task