Suzetrigine for Pain After Non-Mastectomy Breast Surgery

This study is looking at how well a medication called suzetrigine works to manage pain after breast surgery that is not a mastectomy. You might be able to join if you are at least 18 years old, having breast surgery that is expected to cause at least moderate pain, and will also receive a nerve block (a shot to numb an area). The study will give you seven 50 mg tablets of suzetrigine before your surgery. Researchers will measure your worst pain level for the first three days after your surgery to see how effective suzetrigine is. This study is currently unclear on its recruitment status and plans to enroll 120 participants.

Study design
This is a single-center study planning to enroll 120 participants. It is an interventional study, meaning participants will receive a specific treatment.
What's involved
You would receive suzetrigine tablets before surgery and have your pain levels measured for the first three days after surgery. You will also have standard procedures like a urine test if you can become pregnant, and a nerve block.
Compensation
Not stated in the trial record.
Follow-up
Your pain levels will be measured for the first three days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07463430

Suzetrigine for Non-Mastectomy Breast Surgery

Enrolling by Invitation
PHASE4Ages 18+InterventionalTreatment
University of California, San Diego
~120 participants
Updated 2026-04-29 on ClinicalTrials.gov
What's tested:suzetrigine

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Worst pain level first 3 postoperative days
Measured over postoperative days 1-3
Pain, Acute Postoperative
Breast Disease
1 sites across 1 states
California1
  • Brian M Ilfeld, MD, MS · PRINCIPAL_INVESTIGATOR · University of California, San Diego

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Worst pain level first 3 postoperative dayspostoperative days 1-3

    The numeric rating scale (NRS) is a highly-sensitive measure of pain intensity with numbers ranging from 0 to 10, zero equivalent to no pain and 10 equivalent to the worst imaginable pain. The primary outcome measure will be the median value of each participant's worst daily NRS collected on postoperative days 1, 2, and 3 (both the active treatment and historic controls).