AI-Enhanced Peer Review for Prostate Cancer Radiation Therapy

This study is testing a new Artificial Intelligence (AI) tool designed to improve patient safety during radiation therapy for prostate cancer. The tool helps doctors and other staff review treatment plans before you start therapy. It works by highlighting summaries of how different providers plan treatments and pointing out important signals or warning signs. The goal is to help reviewers catch potential mistakes earlier, reduce errors, and make radiation therapy safer. This study will enroll 207 participants, including both healthcare providers and patients with prostate cancer receiving radiation therapy. The main way they will measure success is by looking at the percentage of patients whose lymph node (nodal) volume contours (outlines of the lymph nodes) change during the review process.

Study design
This interventional study plans to enroll 207 participants, including healthcare providers and prostate cancer patients. It is designed to test the impact of an AI tool on the peer review process for radiation therapy planning.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, changes in nodal volume contours, is measured at Baseline, but the duration of follow-up is not specified.

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NCT07463833

Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

Recruiting
NAAges 18+InterventionalHealth services
UNC Lineberger Comprehensive Cancer Center
~207 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:The Artificial Intelligence (AI)/ Machine Learning (ML) contribution to treatment planning

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of patients with changes nodal volume contours
Measured over Baseline
Cancer
Prostate Cancer
1 sites across 1 states
North Carolina1
  • Lukasz Mazur, PhD · PRINCIPAL_INVESTIGATOR · UNC Lineberger Comprehensive Cancer Center

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Eligibility criteria

Inclusion

≥18 years
Peer-review attendees at participating clinics
≥18 years
All patients with prostate cancer radiation therapy cases treated at participating sites (no intervention delivered to patients)
  • Percentage of patients with changes nodal volume contoursBaseline

    Percentage of patients with documented changes regarding nodal volume contours after Artificial Intelligence (AI) enhanced peer review.