STABLE Pilates for Hypermobility

{ "Pilates for Hypermobility Study", "This study is exploring whether a 6-week Pilates exercise program, led by a physical therapist, can help manage symptoms like pain in people with Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), or Hypermobile Spectrum Disorder. Pilates is a gentle exercise focusing on muscle control, posture, and breathing, which may improve strength and stability. You might be able to join if you are 18 or older, have self-reported hypermobility with persistent pain for at least 3 months, and can get on and off the floor without help. The study will look at how practical and acceptable this Pilates program is for participants. The current recruitment status is unclear, and the study plans to enroll 100 participants.", "design": "This interventional study plans to enroll 100 participants. It is testing a Pilates-based exercise program and educational seminars.", "commitments": "You would participate in a 6-week Pilates-based exercise program. The study will also assess your progress at the end of the intervention and at a 12-week follow-up.", "compensation": "Not stated in the trial record.", "follow_up": "Participants will be followed up at 12 weeks after the start of the intervention.", }

Study design
Not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07464093

STABLE Pilates for Hypermobility

Recruiting
NAAges 18+InterventionalTreatment
Brigham and Women's Hospital
~100 participants
Updated 2026-08-19 on ClinicalTrials.gov
What's tested:PilatesEducation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Intervention Feasibility
Measured over Enrollment to end of intervention (week 6) and follow-up (week 12)
+1 more outcome measured
Ehlers-Danlos Syndrome (EDS)
Hypermobile EDS (hEDS)
Hypermobile Spectrum Disorder
1 sites across 1 states
Massachusetts1
  • Samantha Meints, PhD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital

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Eligibility criteria

Inclusion

≥ 18 years old;
Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
Self-reported persistent pain ≥ 3 months;
A minimum of 3/10 self-reported pain intensity in the past week
Able to get on and off the floor without assistance;
Able to communicate fluently in English; and
Able to provide written, informed consent

Exclusion

Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
Recent surgery or acute bone, joint or nerve injury (\<6 months);
Have a history of a severe or progressive neurological or movement disorder;
Pregnant, planning to become pregnant during the study, or currently breast feeding;
Unable to get on and off the floor without assistance;
Unable to complete study procedures due to cognitive impairment;
Unable to provide written, informed consent; or
Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.
  • Intervention FeasibilityEnrollment to end of intervention (week 6) and follow-up (week 12)

    Recruitment, Retention, Attendance

  • AcceptabilityEnrollment to end of intervention (week 6)

    Treatment Helpfulness Questionnaire (THQ): The THQ is a single-item measure that evaluates the perception of helpfulness of an intervention. Participants will be asked to rate the helpfulness of the intervention to which they are randomized on a scale of -5 (extremely harmful) to 5 (extremely helpful) with 0 indicating "neutral."