Michigan Weight Navigation Program (MiWeigh) Study for Obesity

This study, called MiWeigh, is looking at whether a program called MiWeigh helps people lose more weight than receiving general information about weight loss. The MiWeigh program involves a baseline assessment (survey, blood draw, body measurements) and access to a website with weight-loss options, plus at least one visit with a doctor specializing in obesity. You may be eligible if you are between 18 and 75 years old, have a Body Mass Index (BMI) of 30 or higher, and have conditions like Type 2 Diabetes or high blood pressure. The main goal is to see how much weight participants lose over 12 months. The study aims to help people manage or reverse obesity-related health issues.

Study design
This is an interventional study planning to enroll 500 participants. Participants will be assigned to either the MiWeigh program or Enhanced Usual Care.
What's involved
You would complete assessments at baseline and 12 months, including a survey, blood draw, and body measurements. Those in Enhanced Usual Care also complete a survey at 6 months.
Compensation
Not stated in the trial record.
Follow-up
Your body weight will be measured from baseline to 12 months.

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NCT07465341

Michigan Weight Navigation Program (MiWeigh) Study

Recruiting
NAAges 18–75InterventionalTreatment
University of Michigan
~500 participants
Updated 2026-06-12 on ClinicalTrials.gov
What's tested:MiWeighEnhanced Usual Care (EUC)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Mean change in body weight in kilograms from baseline to 12 months.
Measured over Baseline to 12 months
Obesity
1 sites across 1 states
Michigan1
  • Dina Griauzde, MD, MSc · PRINCIPAL_INVESTIGATOR · University of Michigan

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Body Mass index (BMI) 30 kilogram per square meter or higher
Diagnosed with one or more of the following weight-related conditions:
Type 2 Diabetes
Prediabetes Mellitus
Hyperlipidemia (HLP)
Hypertension (HTN)
Polycystic Ovary Syndrome (PCOS)
Obstructive Sleep Apnea (OSA) and/or
Metabolic dysfunction-associated steatotic liver disease (MASLD)
Speaks English
Interest in losing weight
Willingness to complete assessments per study protocol
Willing and able to use the Electronic health records patient portal to respond to messages
Willing to report weight weekly by text if randomized to intervention arm
Able to see provider virtually at certain days/times up to four times in a year

Exclusion

≥ 5% weight loss within the prior 12 months
Has had a Weight Navigation Program visit in past
Pregnant, planning a pregnancy, or breastfeeding in the next year
Ongoing participation in another weight-loss program
Taking an anti-obesity medication
Ever diagnosed with Type 1 Diabetes Mellitus (per protocol)
Dementia
Serious uncontrolled mental health conditions as indicated (per protocol)
Chronic kidney disease, Stage 4 or higher
Alcohol dependence and opioid dependence (per protocol)
History of anorexia or bulimia
Bariatric/ gastric bypass surgery, gastric sleeve surgery, or gastric balloon procedure in last year
Currently enrolled in an interventional research study that is examining how a diet, program, or drug might: promote physical exercise, healthy eating habits, or weight loss; lower blood pressure; or lower blood sugar
Not planning to live in local area over the next year
Intensive cancer treatment such as bone marrow transplant, chemotherapy, radiation, or cancer related surgery (not including hormonal chemotherapy like Tamoxifen) in last six months or next 12 months
Other serious health issues or personal concerns that could prevent participant from completing study
  • Mean change in body weight in kilograms from baseline to 12 months.Baseline to 12 months