INITIATE-HF: Iron Deficiency in Heart Failure

This study, called INITIATE-HF, is looking at whether reminding doctors about guidelines for treating iron deficiency in adults with heart failure (when the heart can't pump enough blood) helps more patients get intravenous (IV) iron (iron given directly into a vein). You could be eligible if you are an adult (over 18) with heart failure, have a specific type of heart failure (left ventricular ejection fraction less than 50%), are currently in the hospital, and have iron deficiency (TSAT less than 20%). The study will compare two groups of medical centers: one where doctors are notified about iron deficiency guidelines and one where they are not. The main goal is to see what percentage of patients receive IV iron within 7 days of being admitted to the hospital.

Study design
This is an interventional study involving 3000 participants. It's a cluster randomized controlled trial, meaning medical centers are randomly assigned to either receive notifications or not.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured within 7 days of confirmed eligibility.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07467668

Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure

Recruiting
NAAges 18+Interventional
Kaiser Permanente
~3,000 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:Notification GroupNo Notification Group

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
% of patients receiving IV iron within 7 days of hospital admission
Measured over From the day of confirmed eligibility up to 7 days later
Iron Deficiency (ID)
Heart Failure
Heart Failure and Reduced Ejection Fraction
Heart Failure and Mildly Reduced Ejection Fraction

NCT07467668

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Division of Research

    Pleasanton, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • % of patients receiving IV iron within 7 days of hospital admissionFrom the day of confirmed eligibility up to 7 days later

    The primary outcome is the implementation outcome of the percentage of patients who receive IV iron within 7 days of hospitalization to determine how the provider-facing notification influences provider behavior and care processes.