Study of GXV813 for Hospitalized Adults with Schizophrenia

This study is testing a drug called GXV813 to see if it is safe, tolerable, and effective for adults hospitalized with schizophrenia. You might be able to join if you are between 18 and 65 years old and have a diagnosis of schizophrenia. Participants will receive either GXV813 or a placebo (an inactive substance). Researchers will measure how your symptoms change using a tool called the Positive and Negative Symptom Scale (PANSS) over 6 weeks to see if GXV813 helps. The study is currently unclear about its recruitment status and plans to enroll 142 participants.

Study design
This is an interventional study involving 142 planned participants. It compares the drug GXV813 to a placebo.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at Week 6.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07467993

Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

Recruiting
PHASE2Ages 18–65InterventionalTreatment
Novartis Pharmaceuticals
~142 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:GXV813Placebo

At a glance

Recruiting sites
16 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in Positive and Negative Symptom Scale (PANSS) total score
Measured over Baseline, Week 6
Schizophrenia
16 sites across 8 states
Bulgaria8
Illinois2
Arkansas1
California1
Florida1
Georgia1
Missouri1
BGR1

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  • Change from baseline in Positive and Negative Symptom Scale (PANSS) total scoreBaseline, Week 6

    PANSS is a 30-item rating scale used to assess the positive, negative, and general psychopathy symptoms of schizophrenia. PANSS total score ranges from 30 to 120 , where a higher score indicates greater severity.