Exercise and Protein Efficiency in Type 2 Diabetes
This study is looking at how a 12-week exercise program affects how your body uses protein if you have Type 2 Diabetes (T2D). Researchers will compare 15 older adults (65 years or older) with T2D to 15 older adults without T2D. The exercise program involves moderate-to-vigorous aerobic and strength training 2-3 times a week. The main goal is to understand how exercise changes protein efficiency in people with T2D. To join, you must be at least 65 years old, have a BMI between 25-40, and not have done structured exercise in the past 6 months. If you have T2D, you need a physician diagnosis with an HbA1c (a measure of blood sugar over time) greater than 6. The current recruitment status is unclear.
- Study design
- This is a randomized controlled trial involving 30 participants, split into two groups: 15 with Type 2 Diabetes and 15 without. Participants will undergo a 12-week exercise program.
- What's involved
- You would participate in a 12-week progressive exercise training program 2-3 times per week. This includes pre- and post-testing with body composition measures, glucose tolerance tests, fitness tests, and dietary protein efficiency assessments involving drinks, urine, and breath samples.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured from enrollment to the end of the 12-week intervention, so follow-up is for 12 weeks.
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Exercise and Protein Efficiency in T2D
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Inclusion
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What this trial measures
- Define how exercise modifies protein efficiency in T2DFrom enrollment to end of 12-week intervention
Define how exercise modifies protein efficiency by assessing whole-body net protein balance via amino acid oxidation rates in response to protein intake of 1.0 g protein/kg/d. We expect to observe elevated baseline (pre-training) rates of oxidative excretion in aging T2D compared with CON. Following 12 weeks of exercise, both groups will improve their whole-body net protein balance, (indicative of lower oxidation rates), but the largest effects will be observed in the T2D vs CON group