NCT07483164
A Study Of T1/Tref Intubating Conditions
Enrolling by Invitation
NAAges 18+InterventionalMayo ClinicInvestigator-initiated
~108 participants
Updated 2026-07-20 on ClinicalTrials.gov
What's tested:Twitch amplitude <0.1Twitch amplitude <0.3Twitch amplitude <0.5
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Maximum T1/Tref ratio associated with excellent intubating conditions
Measured over Baseline
Conditions
Where it's being run
1 sites across 1 statesFlorida1
Study leadership
- J. Ross Renew, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Age \> or = 18 years old
Patients willing to participate and provide an integrated, informed consent
Exclusion
Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis.
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment requiring dialysis or end-stage liver disease.
Patients requiring a rapid sequence induction for airway protection.
Patients deemed ineligible for surgery, including pregnancy (as determined by standard of care testing).
What this trial measures
- Maximum T1/Tref ratio associated with excellent intubating conditionsBaseline
The T1/Tref ratio that leads to the highest proportion of patients being intubated under excellent conditions: T1/Tref \<0.1, T1/Tref \<0.3, or T1/Tref \<0.5