Study on Postpartum Depression and Alcohol Use in New Mothers

This study is looking at how a program called Contingency Management & Problem Solving Therapy (CM-PST) might help new mothers with postpartum depression and alcohol use. CM-PST is a 6-week online course with video calls and at-home drug testing. Researchers want to see if this program can reduce depression symptoms and alcohol use compared to usual care. You could join if you are a woman, at least 18 years old, and within 12 months of giving birth. The study aims to enroll about 30 mothers. Success will be measured by changes in depression symptoms and alcohol use over three months. The study status is currently unclear.

Study design
This is an interventional study where about 30 new mothers will be randomly assigned to either receive the CM-PST intervention or continue with their usual care.
What's involved
If you participate, you would either attend a 6-week online CM-PST course with weekly at-home drug testing, or continue with your standard postpartum care. Your depression symptoms and alcohol use will be checked at the start, weekly (for alcohol), and at 3 months.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be followed for 3 months after the start of the study.

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NCT07485036

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms

Not Yet Recruiting
NAAges 18+InterventionalTreatment
University of Illinois at Chicago
~30 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:Contingency Management & Problem Solving TherapyUsual Care

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in postpartum depression symptoms
Measured over Screening, Baseline, 3 months
+5 more outcomes measured
Postpartum Depression (PPD)
Alcohol Use
Contingency Management
Problem Solving Therapy
1 sites across 1 states
Illinois1

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Eligibility criteria

Inclusion

Biologically female
Age ≥18 years
Within 12 months postpartum
Able to provide informed consent

Exclusion

Serious medical or psychiatric conditions requiring hospitalization
Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychiatric disorder
Current use of psychoactive drugs, medication to treat problematic alcohol use, or depression
Participation in past 6 months in problematic alcohol use or substance use treatment
Unable to provide consent
  • Change in postpartum depression symptomsScreening, Baseline, 3 months

    Participants will take the Edinburgh Postnatal Depression Scale (EPDS) at screening, baseline and at 3 months to assess changes in mental health and depressive symptoms. This is reported on a scale of 0-30; a higher score indicates a higher likelihood of postpartum depression.

  • Alcohol use test resultsBaseline, Weekly, 3 months

    Participants' alcohol use will be monitored and assessed with urine drug tests at baseline, 2x weekly throughout the duration of the 6-week intervention, and at 3 months.

  • Change in alcohol use screening statusScreening, Baseline, 3 months

    Participants will take the Alcohol Use Disorders Identification Test (AUDIT) at the time of screening, baseline and at 3 months. This is reported on a scale of 0-40; a higher score indicates a higher likelihood of moderate to severe alcohol use.

  • Change in alcohol-related negative consequencesBaseline, 3 months

    Participants will take the Rutgers Alcohol Problems Index (RAPI) at baseline and at 3 months to assess changes in problems related to alcohol use. This is reported on a scale of 0-72; a higher score indicates a higher likelihood of alcohol-related negative consequences in everyday life.

  • Change in alcohol useBaseline, 3 months

    Participants will take the Timeline Follow Back (TLFB) questionnaire at baseline and at 3 months to assess changes in alcohol use.

  • Change in reasons for drinkingBaseline, 3 months

    Participants will take the Drinking Motive Questionnaire-Revised (DMQ-R) at baseline and at 3 months to assess changes in alcohol use motivations. This is reported on a scale of 20-100; a higher score indicates stronger motivations for alcohol use.