Studying Blood Flow During CABG Surgery

This study is looking at a tool called Transit-Time Flow Measurement (TTFM) during coronary artery bypass graft (CABG) surgery. CABG is a type of heart surgery where new paths are created for blood to flow around blocked arteries to the heart. TTFM uses sound waves to check how well blood is flowing through these new paths during surgery. The goal is to see if using TTFM to assess blood flow during surgery helps the new blood vessels (grafts) stay open and improves how patients recover. The study will enroll 1242 participants who are at least 18 years old and having their first, non-emergency CABG surgery. The main way to measure success is to see if any grafts fail within 1 to 3 months after surgery. The current status of this study is unclear.

Study design
This is an interventional study designed to evaluate the impact of TTFM on clinical outcomes in a large randomized group of 1242 participants.
What's involved
You would need to be willing and able to provide written informed consent and complete all study procedures, including quality of life questionnaires.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for graft failure at 1 to 3 months after their CABG surgery.

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NCT07485738

The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery

Recruiting
NAAges 18+InterventionalPrevention
Weill Medical College of Cornell University
~1,242 participants
Updated 2026-04-22 on ClinicalTrials.gov
What's tested:Transit-Time Flow Measurement (TTFM)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Any Graft Failure
Measured over 1 to 3 months after index CABG
CABG Graft Integrity
CABG
Blood Flow
Transit-time Flow Measurement
Heart Disease
1 sites across 1 states
New York1
  • Mario Gaudino, MD, PhD, MSCE, FEBCTS, FACC · PRINCIPAL_INVESTIGATOR · Weill Medical College of Cornell University

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  • Any Graft Failure1 to 3 months after index CABG

    The primary outcome of SMARTFLOW:Patency is any graft failure