XytriX for Knee Osteoarthritis Study

This study is looking at the safety and effectiveness of XytriX, a treatment made from umbilical cord stem cells, for people with knee osteoarthritis. You might be able to join if you are an adult aged 18 or older with Grade I-IV knee osteoarthritis, which means your doctor has confirmed it with an X-ray. You also need to have had knee osteoarthritis symptoms for at least three months and be able to walk. The researchers will measure how well XytriX works by looking at your knee pain and function using two common scores (Knee Injury and Osteoarthritis Outcome Score and Western Ontario and McMaster Universities Osteoarthritis Index) after 24 months. The current status of this study is unclear, and it plans to enroll 75 participants.

Study design
This study is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 75 participants.
What's involved
Participants will receive a single injection of mesenchymal stem cells into the affected knee joint.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 months after treatment to assess the long-term effects of XytriX.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07487766

The Safety and Efficacy of XytriX (Umbilical Cord-Derived Mesenchymal Stem Cells) in the Treatment of Knee Osteoarthritis

Not Yet Recruiting
PHASE1Ages 18+InterventionalTreatment
TricelX Inc.
~75 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:Mesenchymal Stem Cell Injection

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Knee Injury and Osteoarthritis Outcome Score
Measured over 24 months
+1 more outcome measured
Osteoarthritis
1 sites across 1 states
Texas1

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  • Knee Injury and Osteoarthritis Outcome Score24 months

    Scores are transformed into a 0-100 point scale. 0 means extreme problems and 100 means no problems.

  • Western Ontario and McMaster Universities Osteoarthritis Index24 months

    Items are typically scored on a 0-4 Likert scale: None (0), Mild (1), Moderate (2), Severe (3), and Extreme (4). Lower scores indicate better outcomes, while higher scores indicate worse pain, stiffness, and functional limitations.