Understanding Quality of Life in ALS Patients at TidalHealth

This study at TidalHealth aims to understand how physical abilities and other factors affect the quality of life for people living with Amyotrophic Lateral Sclerosis (ALS), also known as Motor Neuron Disease. Researchers will use two questionnaires: the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) to measure physical function, and the Amyotrophic Lateral Sclerosis Assessment Questionnaire-40 (ALSAQ-40) to measure quality of life. The goal is to identify what most impacts a patient's daily life, which could help improve care. You may be able to join if you are over 18, have an ALS diagnosis, and receive care at the TidalHealth Peninsula Regional Multidisciplinary ALS Clinic. The study plans to enroll 30 participants, but its current status is unclear.

Study design
This is an observational study, meaning researchers will collect information over time without giving any new treatments. It plans to include 30 participants.
What's involved
You would complete questionnaires at your initial visit and then at every other standard-of-care clinic visit for up to two years.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life will be assessed for up to two years, and your physical functioning will be assessed for up to two years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07491484

Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth

Recruiting
Not specifiedAges 18+Observational
TidalHealth, Inc.
~30 participants
Updated 2026-03-24 on ClinicalTrials.gov
What's tested:Amyotrophic Lateral Sclerosis Functional Rating Scale-RevisedAmyotrophic Lateral Sclerosis Assessment Questionnaire-40

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Results of the Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40)
Measured over Assessment will start at the initial visit, then every other standard-of-care clinic visit, through study completion (assessed up to 2 years).
+1 more outcome measured
Amyotrophic Lateral Sclerosis
Motor Neuron Disease

NCT07491484

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • TidalHealth Peninsula Regional, Inc.

    Salisbury, Marylandstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

Over the age of 18
Have a diagnosis of Amyotrophic Lateral Sclerosis of Motor Neuron Disease
Able to comprehend and willing to sign an informed consent form and comply with study procedures.
Receiving care at TidalHealth Peninsula Regional Multidisciplinary ALS Clinic

Exclusion

Unable to read and understand English
Unwilling or unable to comply with the study procedure, including the presence of any condition that is likely to affect the participant's ability to comply with study procedures.
  • Results of the Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40)Assessment will start at the initial visit, then every other standard-of-care clinic visit, through study completion (assessed up to 2 years).

    Participants report a response related to their overall health condition during the past two weeks; all answers are given on a five-point Likert Scale. Where 0 indicates best health status and 4 indicates worst.

  • Results of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R)Assessment will start at the initial visit, then every standard-of-care clinic visit, through study completion (assessed up to 2 years).

    Participants report a response related to their functional status; all answers are given on a four-point Likert Scale. Where 0 indicates maximum disability and 4 indicates normal function.