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Study of Steroid Injections for Back Pain

This study is looking at different doses of steroid injections to treat lower back pain that spreads to the legs (lumbar radiculopathy or sciatica). Researchers want to see if different doses of Triamcinolone (10 mg, 40 mg, or 80 mg) or Dexamethasone (2 mg or 4 mg) injections are better at reducing pain and improving your quality of life. You might be able to join if you are an adult with MRI-confirmed lumbar radiculopathy, haven't had back surgery, and don't take strong pain medication. The study will measure your pain levels at the start, and then again 2 weeks and 6 weeks after the injection. The study is currently unclear on its status and plans to enroll 150 participants.

Study design
This interventional study plans to enroll 150 adult participants. It compares different doses of Triamcinolone and Dexamethasone injections for back pain.
What's involved
You would receive a single steroid injection in your lower back. Your pain intensity will be measured before the injection and then again at 2 weeks and 6 weeks afterward.
Compensation
Not stated in the trial record.
Follow-up
Your pain levels will be checked for up to 6 weeks after the injection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07494136

Dose Dependent Steroid Injections

Not Yet Recruiting
PHASE4Ages 18+InterventionalTreatment
University of Miami
~150 participants
Updated 2026-08-12 on ClinicalTrials.gov
What's tested:Triamcinolone 10 Mg/mL Injectable SuspensionTriamcinolone 40 Mg/mL Injectable SuspensionTriamcinolone 80 Mg/mL Injectable SuspensionDexamethasone 2 MGDexamethasone 4mgDexamethasone 8 MG

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pain Intensity (Numeric Rating Scale 0-10) (NRS)
Measured over Baseline (pre-procedure), 2 weeks post-procedure (±1 week), 6 weeks post-procedure (±2 weeks)]

Conditions

Lumbar Radiculopathy
Sciatica
Back Pain With Radiation

Explore related trials

Lumbar radiculopathy

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Seyed A mostoufi, MD · PRINCIPAL_INVESTIGATOR · Christine E. Lynn Rehabilitation Center

Who to contact

Nareka Trewick, MD
[email protected]
305-243-6605
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults able to consent
Lumbar radiculopathy with MRI-confirmed pathology
No history of back surgery
Use of interlaminar approach lumbar spine injections
No use of oral pain medication other than Tylenol or Acetaminophen during the 6 weeks after injection

Exclusion

Adults unable to consent
Individuals who are not yet adults (infants, children, teenagers)
Pregnant women
History of back surgery
Use of oral pain meds other than Tylenol or Acetaminophen during the 6 weeks after injection

What this trial measures

  • Pain Intensity (Numeric Rating Scale 0-10) (NRS)Baseline (pre-procedure), 2 weeks post-procedure (±1 week), 6 weeks post-procedure (±2 weeks)]

    Pain intensity will be measured using the Numeric Rating Scale (NRS), a validated 0-10 verbal rating scale in which participants rate their pain on a continuum from 0 (pain) to 10 (max pain). Higher scores indicate greater pain severity.