Abenacianine for Lung Cancer Surgery
This study is looking at a drug called Abenacianine (VGT-309) to help doctors find cancer during lung surgery. Abenacianine is given through an IV and works with a special camera (Near Infrared or NIR imaging) to highlight cancer cells. The goal is to see how well Abenacianine helps identify cancer and if it's safe. You might be able to join if you are at least 18 years old and are scheduled for lung surgery to remove a lesion or mass. The study aims to enroll about 132 participants. The study status is currently unclear.
- Study design
- This is a Phase 3, multi-center study that will compare participants receiving Abenacianine with NIR imaging to a control group receiving Abenacianine without NIR imaging. Approximately 132 participants will be enrolled.
- What's involved
- You will receive Abenacianine through an IV and undergo NIR imaging during your lung surgery. The primary endpoint is measured on the day of surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome is measured on the day of surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
At a glance
Conditions
Where it's being run
9 sites across 8 statesStudy leadership
- Curtis Scribner, MD · STUDY_DIRECTOR · Vergent Bio
Who to contact
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What this trial measures
- Identify the proportion of participants with at least one Clinically Significant Event (CSE) as defined by:Day of Surgery
A. Intraoperative localization of one or more preoperatively identified lung lesions using abenacianine with NIR imaging when standard surgical techniques using white light with or without palpation fail to identify the lesion(s). B. Identification of one or more synchronous or occult lung lesions using abenacianine with NIR imaging when standard surgical techniques using white light with or without palpation and preoperative imaging fail to identify the lesion(s).