This pilot study is testing if a steroid cream, betamethasone valerate 0.1%, could help prevent repeat urinary tract infections (UTIs) in uncircumcised male infants. The main goal is to see how well we can recruit families for a larger study in the future. Infants up to 5 months old who have had their first UTI with a fever can join. You would apply either the steroid cream or a placebo cream (a cream without medicine) to your baby's foreskin and glans twice a day for four weeks. The study will then follow your baby to see if they get more UTIs and to understand your experience.

Study design

This is an interventional pilot study planning to enroll 40 uncircumcised male infants. Participants will be randomly assigned to receive either the active drug or a placebo.

What's involved

Participants will apply cream twice a day for four weeks. There will be two follow-up visits: one 28-38 days after enrollment/discharge, and another 6-7 months after enrollment/discharge.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 6-7 months after enrollment or hospital discharge to check for UTIs and gather parent feedback.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.