Nurse-Led Support for Triple-Negative Breast Cancer Survivors

This study is testing a new nurse-led support program called RESTORE for people who have recently completed treatment for triple-negative breast cancer (TNBC). TNBC is a type of breast cancer that can be more challenging to treat. The RESTORE program is a virtual (online) group therapy that teaches coping skills, problem-solving, and relaxation techniques. Participants will either join the RESTORE program or receive educational information about breast cancer survivorship. The main goal of this study is to see if the RESTORE program is practical and well-received by patients, and if it can help improve quality of life, anxiety, and fear of cancer returning. You may be able to join if you are an adult (18 or older) diagnosed with stage 1-3 TNBC, are between one and 12 months after your curative treatment, and are experiencing some distress.

Study design
This study is a pilot randomized controlled trial with 75 participants. Participants will be randomly assigned to either the RESTORE program or enhanced usual care.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will track program feasibility, such as enrollment, retention, and session attendance, for 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07513311

A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer

Recruiting
NAAges 18+InterventionalSupportive care
Massachusetts General Hospital
~75 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:RESTOREEnhanced Usual Care

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Program Feasibility - Enrollment
Measured over 12 weeks
+3 more outcomes measured
Triple Negative Breast Cancer (TNBC)
1 sites across 1 states
Massachusetts1
  • Kathryn E Post, PhD, RN, ANP-BC · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Diagnosis of stage 1-3 triple-negative breast cancer
Age ≥ to 18 years
Between one and 12 months post curative therapy
Reporting distress at least 4/10 on a one-item screener
Ability to read and respond in English or Spanish

Exclusion

Patients with stage 4 cancer
Patients with impaired cognition or serious mental illness that would preclude participation in study procedures
  • Program Feasibility - Enrollment12 weeks

    The investigators will evaluate program feasibility by examining enrollment metrics. Enrollment feasibility is defined as ≥ 60% of eligible, approached patients who were offered study participation enrolling in the study.

  • Program Feasibility - Retention12 weeks

    The investigators will evaluate program feasibility by examining retention rates. Retention feasibility is defined as ≥ 70% of participants completing the 12-week follow-up assessment.

  • Program Feasibility - Session Attendance12 weeks

    The investigators will evaluate program feasibility by examining session attendance. Attendance feasibility is defined as ≥ 70% of participants completing at least 4 of 5 RESTORE intervention sessions.

  • Intervention Acceptability12 weeks

    The investigators will evaluate intervention acceptability by examining satisfaction scores on the Client Satisfaction Questionnaire (CSQ). The intervention will be deemed acceptable if ≥75% of participants report average satisfaction scores above the CSQ's midpoint. The CSQ is evaluated on a 1-4 scale, with higher scores indicating greater satisfaction.