Oral Gallium Maltolate for Recurrent Glioblastoma

This study is looking at a drug called Gallium Maltolate for people with recurrent glioblastoma (a type of brain cancer that has come back). Researchers want to see how well Gallium Maltolate gets into the brain and into the tumor. You would take Gallium Maltolate by mouth for about two weeks. After that, you would have a surgical procedure, like a needle biopsy or tumor removal, if your medical team thinks it's necessary. The main goal is to measure differences in the tumor tissue after 3 months. This is a small study, planning to include 8 participants who are at least 18 years old. The current status of the study is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It is a Phase 0 study, and the planned enrollment is 8 participants.
What's involved
You would take Gallium Maltolate daily for about 14 days. After this, you would have a surgical procedure (needle biopsy or resection) if your clinical team determines it's needed.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, Glioma Tissue Difference, is measured at 3 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07515924

Oral Gallium Maltolate for Recurrent Glioblastoma

Not Yet Recruiting
EARLY_PHASE1Ages 18+InterventionalTreatment
Medical College of Wisconsin
~8 participants
Updated 2026-04-07 on ClinicalTrials.gov
What's tested:Gallium MaltolateSurgical Intervention

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Glioma Tissue Difference
Measured over 3 months
Glioblastoma
1 sites across 1 states
Wisconsin1
  • Rupen Desai, MD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin
Medical College of Wisconsin Cancer Center Clinical Trials Office
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

  • Glioma Tissue Difference3 months

    The difference in gallium concentration between glioma tissue resected from patients treated with gallium maltolate and matched glioma tissue from untreated patients from a tumor bank registry, matched based on age, pathology, and gender. The measure type will be mean reported with standard deviation.