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Comparing Lasers for Kidney Stone Treatment

This study is comparing two types of lasers, the Thulium:YAG laser and the Moses Holmium:YAG laser, which are commonly used to treat kidney stones during a procedure called ureteroscopy. Researchers want to see how effective and safe each laser is at breaking up stones. You might be able to join if you are 18 or older and have a kidney stone between 7 and 20 millimeters in size, or multiple stones that add up to that size. The main goal is to see how many people are completely stone-free one month after treatment. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 70 participants to compare two different laser treatments for kidney stones.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed up for one month after their treatment to check for remaining stone fragments.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07516106

Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths

Not Yet Recruiting
NAAges 18+InterventionalTreatment
NYU Langone Health
~70 participants
Updated 2026-04-07 on ClinicalTrials.gov
What's tested:Moses Holmium:YAG laserThulium:YAG laser

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Stone-free rate (absence of any fragments ≥ 2mm)
Measured over Month 1
+1 more outcome measured

Conditions

Kidney Stone

Explore related trials

Nephrolithiasis

Where it's being run

2 sites across 2 states
Arizona1
New York1

Study leadership

  • Esteban Emiliani, MD, PhD · PRINCIPAL_INVESTIGATOR · NYU Langone Health

Who to contact

Esteban Emiliani, MD, PhD
[email protected]
646-290-4549
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Solitary renal stone 7 to 20 mm in size or in the case of multiple stones the conglomerate diameter (additive maximal diameter of all stones on axial imaging of computed tomography) of 7-20 mm is required
Must be a suitable operative candidate for flexible ureteroscopy per American Urological Association guidelines
Must be 18 years or older
Must be able to give consent
Bilateral ureteroscopy will be permitted , but only the side(s) where the FANS access sheath was used (per surgeon discretion) will be included in the study, however can include both sides as separate units. Subjects will be enrolled only once in the study. No subject will be enrolled more than a single time. For patients undergoing bilateral ureteroscopy, each kidney will be considered a separate unit for stone-related assessments. Peri-patient measures, such as operative time, will be recorded at the patient level. Bilateral cases will be clearly identified and handled consistently to ensure accurate and appropriate interpretation of study outcomes.
Must be a patient of one of the surgeons participating in this study.

Exclusion

Concomitant stones in the ureter
Prior radiotherapy to the abdomen or pelvis
Neurogenic bladder or spinal cord injury
Pregnancy
Untreated urinary tract infection (UTI)
Anatomical abnormalities (including, but not limited to, bifid system, pelvic kidney, horseshoe kidney)
Prior ipsilateral upper urinary tract reconstructive procedures or history of ipsilateral ureteral stricture

What this trial measures

  • Stone-free rate (absence of any fragments ≥ 2mm)Month 1
  • Zero stone-free rate (absence of any residual fragments confirmed by negative CT scan postoperative at one month)Month 1