ASSIST Study: Substance Use Screening for Childhood Cancer Survivors

This study, called the ASSIST Study, is looking at whether a brief substance use screening and counseling approach can be easily added to the regular care for adult survivors of childhood cancer at St. Jude Children's Research Hospital. You would complete a short questionnaire called WHO ASSIST v3.1 Screening, which asks about your use of tobacco, alcohol, cannabis, and other substances. If your results show a moderate or high risk, you might receive a brief counseling session (ASSIST Linked Brief Intervention) using motivational interviewing to help you think about your substance use. The study aims to enroll 30 participants to see if this approach is practical and acceptable in a clinic setting. Success for this study means showing that the screening and intervention are feasible to use.

Study design
This is an interventional study with an unclear status, planning to enroll 30 participants. It is designed to test the feasibility of incorporating a standardized substance use measure and brief intervention.
What's involved
You would complete the WHO ASSIST v3.1 Screening questionnaire during a regularly scheduled psychosocial visit. If assigned to the intervention group and screening moderate/high risk, you would receive a brief counseling session during the same appointment. You will also complete a follow-up survey three months later.
Compensation
Not stated in the trial record.
Follow-up
Participants will complete a follow-up survey three months after the initial screening and intervention.

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NCT07516301

Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

Recruiting
NAAges 15+Interventional
St. Jude Children's Research Hospital
~30 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:WHO ASSIST v3.1 Screening with FeedbackASSIST Linked Brief Intervention (10 Step Motivational interviewing (MI)/FRAMES)WHO ASSIST v3.1 Screening (No Feedback)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Enrollment Feasibility
Measured over Through study completion, an average of 1 year
+5 more outcomes measured
Survivors of Childhood Cancer
Substance Use
1 sites across 1 states
Tennessee1
  • Rachel Webster, PhD · PRINCIPAL_INVESTIGATOR · St. Jude Children's Research Hospital

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Eligibility criteria

Inclusion

Followed in the ACT Clinic at St. Jude Children's Research Hospital
Greater than or equal to 15 years of age at time of evaluation
Able to speak and read English

Exclusion

Significant mental or cognitive impairment that would impact ability to complete surveys or participate in the brief intervention
  • Enrollment FeasibilityThrough study completion, an average of 1 year

    Proportion of participants approached that enroll in the study

  • Screener FeasibilityThrough study completion, an average of 1 year

    Proportion of participants enrolled that completed the substance use screener with their social worker

  • Brief Intervention FeasibilityThrough study completion, an average of 1 year

    Proportion of participants that scored moderate-to-high risk on the substance use screener that received a brief intervention to reduce substance use

  • Care coordination FeasibilityThrough study completion, an average of 1 year

    Proportion of participants that received a referral for additional services received a coordination of care call from their social worker within 48 business hours of their social work visit

  • Screener Acceptability- Acceptability of Intervention MeasureTime 1 (1-week post baseline assessment)

    A measure of intervention acceptability. Scores are summed and range from 4-20, with scores ≥12 indicative of intervention acceptability.

  • Intervention Acceptability - Acceptability of Intervention MeasureTime 2 (3 months post baseline assessment)

    A measure of intervention acceptability. Scores are summed and range from 4-20, with scores ≥12 indicative of intervention acceptability.