Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort
This study is looking for healthy adults, aged 18-65, who usually eat a low-fiber diet. It compares three different dietary fiber supplements: LOAM prebiotic fiber, inulin, and a cellulose placebo. The main goal is to see how these supplements affect intestinal gas (flatus) production and overall digestive comfort. You would take one of these supplements daily for four weeks. Researchers will measure changes in your average daily gas production from the beginning of the study to the end of the first week of taking the supplement. This helps them understand which fiber might be best for gut health.
- Study design
- This interventional study plans to enroll 125 healthy participants. You would be randomly assigned to receive one of the three supplements.
- What's involved
- You would take a daily supplement mixed with water for four weeks. You'd also wear a Ventos device for about 22 hours on two designated days per week for five weeks to monitor intestinal gas.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurement for gas production is taken from the beginning of the study to the end of the first week of supplementation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
What this trial measures
- Change in Average Daily Flatus from Baseline (Week 1) to Week 2, Comparing LOAM Prebiotic Fiber to InulinBaseline (Week 1) to Week 2 (first week of supplementation)
Average daily flatus as measured by the Ventos wearable intestinal gas monitoring device, defined as the mean of Ventos-measured flatus counts obtained on Tuesday and Saturday of each week. The primary analysis compares the change from Week 1 (baseline, no supplementation) to Week 2 (first week of supplementation) between the LOAM and inulin groups using ANCOVA, with baseline average daily flatus as a covariate.