Exercise Study for SCAD and FMD
This study is looking at how different types of exercise, specifically aerobic (like cycling) and resistance exercises, affect people who have experienced Spontaneous Coronary Artery Dissection (SCAD) and/or Fibromuscular Dysplasia (FMD). Researchers want to understand how your heart and body respond to these exercises, and if they impact your symptoms. You might be able to join if you are between 21 and 65 years old, have a history of SCAD or FMD (at least 2 months ago and no chest pain), and are not clinically obese or have conditions that limit exercise. The study aims to see changes in your blood pressure and how well you can do daily activities after exercise. The current status of this study is unclear, and it plans to enroll 28 participants.
- Study design
- This is an interventional study, meaning participants will receive specific exercises. It plans to enroll 28 participants, but the phase is not specified.
- What's involved
- You will undergo three exercise tests, each at least 48 hours apart. These tests include a symptom-limited cardiopulmonary exercise test (CPET) on a bike.
- Compensation
- Not stated in the trial record.
- Follow-up
- Blood pressure will be measured at baseline, 5 minutes, 25 minutes, 50 minutes, and 55 minutes. Other scores are measured at baseline.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Elizabeth H. Dineen, DO · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in blood pressure in response to aerobic exerciseBaseline, 5 minutes, 25 minutes, 50 minutes and 55 minutes
Systemic blood pressure will be measured at rest, at peak exercise, and for 5 minutes of recovery after exercise via finger photoplethysmography and reported as mmHg
- Dartmouth COOP Functional Assessment Chart scoreBaseline
The Dartmouth COOP Functional Assessment Charts are a set of patient-reported, pictorial tools used to measure physical, mental, and social functioning. The tool includes 9 questions that are rated on scores from 1-5, with higher scores indicating worse function.
- Duke Activity Index Status (DASI) scoreBaseline
The Duke Activity Status Index (DASI) is a self-administered questionnaire that measures a patient's functional capacity. It consists of 12 yes/no questions. Scores range from 0 to 58.2, with higher scores indicating better exercise capacity.
- International Physical Activity Questionnaire Short Form (IPAQ-SF) scoreBaseline
The International Physical Activity Questionnaire Short Form (IPAQ-SF) is a 7-item self-reported questionnaire where subjects report time spent being physically active in the last 7 days reported hours per day or minutes per day.
- Change in perceived exertionBaseline, 25 minutes, and 50 minutes
Perceived exertion (breathlessness and leg fatigue) will be obtained using the Borg 0-10 scale.
- Change in blood lactate concentration [La-]bBaseline, 25 minutes, and 50 minutes
Blood lactate concentration \[La-\]b will be measured via analysis of a pinprick point-of-care lactate test (via the earlobe) at rest, during exercise, and at peak exercise.