This study is looking at whether dental cleanings can help prevent chronic graft-versus-host disease (GVHD) in people who have had a stem cell transplant (HCT). HCT is a treatment for some blood cancers, but it can sometimes lead to GVHD, where the new cells attack your body. Some research suggests that bacteria in your mouth might play a role in developing chronic GVHD. This trial will provide a dental cleaning around 28 days after your transplant. Researchers will then see if this helps reduce the chance of developing moderate-to-severe chronic GVHD one year after your transplant. You might be able to join if you are 18 or older, have had a specific type of HCT, and are willing to have a follow-up visit one year later. The current status of this study is unclear, and it plans to enroll 45 participants.

Study design

This is an interventional study planning to enroll 45 participants. It involves a dental cleaning procedure after a stem cell transplant.

What's involved

You would receive a simplified dental cleaning around 28 days after your transplant. You will then have follow-up visits on days +84, +180, and at 1 year.

Compensation

Not stated in the trial record.

Follow-up

Participants are followed up on days +84 and +180, and at 1 year after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.