Adolescent PTSD Study: Understanding Stress Responses
This study is looking for adolescents aged 14-18 who have experienced trauma and have symptoms of Posttraumatic Stress Disorder (PTSD). We want to understand how young people with trauma-related symptoms react to stress and strong emotions. Participants will engage in tasks that involve responding to threats, managing emotions, and repeatedly imagining a stressful event using a technique called "script-driven imagery." We will measure anxiety levels and physical responses like heart rate and muscle activity (Corrugator Supercilii Electromyography or EMG) to see if the repeated imaginal exposure changes these responses over time. We also want to see if how you react to threats and manage emotions at the beginning of the study affects how you respond to the imaginal exposure. A caregiver must be willing to participate with you.
- Study design
- This interventional study plans to enroll 180 participants aged 14-18. It is not specified if the study is randomized or blinded.
- What's involved
- You would participate in experimental tasks, including repeated script-driven imagery tasks, at baseline and 1 week later. Your caregiver would also need to participate.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your anxiety and physiological responses will be measured at baseline and 1 week after baseline.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Predictors & Mechanisms of Adolescent PTSD
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- State Anxiety (State and Trait Anxiety Inventory for Children - State Scale)Baseline (Visit 1, prior to first script-driven imagery task) and 1 week after baseline (Visit 2, following repeated imaginal exposure)
- Corrugator Supercilii Electromyography (EMG) ReactivityDuring script-driven imagery tasks at baseline (Visit 1) and 1 week after baseline (Visit 2)
- Heart Rate Reactivity During Script-Driven ImageryDuring script-driven imagery tasks at baseline (Visit 1) and 1 week after baseline (Visit 2)
- Skin Conductance Reactivity During Script-Driven ImageryDuring script-driven imagery tasks at baseline (Visit 1) and 1 week after baseline (Visit 2)
- Posttraumatic Stress Disorder Symptoms (UCLA PTSD Reaction Index for DSM-5)Baseline (Visit 1) and 1 month after baseline (Visit 3)