MOCHA: Mental Health Care for High-Risk Pregnant and Postpartum Patients

This study, called MOCHA, is looking at a Collaborative Mental Health Care Program (CMHCP) for pregnant and new mothers who are in the hospital for medical reasons. Many patients in this situation experience anxiety, depression, and stress. The CMHCP aims to provide early mental health screening, therapy, and follow-up care to help with these symptoms. Researchers want to see if this program can be successfully offered in a high-risk obstetric unit. You might be able to join if you are 18 or older, pregnant or recently gave birth, have had a difficult pregnancy outcome, are in the hospital for an extended stay, and speak English. The study will measure changes in your depression, anxiety, and post-traumatic stress symptoms from when you enter the hospital until three months after you go home.

Study design
This is an observational study, meaning researchers will watch how the program works. It is a single-arm study, involving about 50 participants.
What's involved
You would complete a mental health questionnaire and may receive individual therapy sessions during your hospital stay. You would also complete short symptom checks after therapy sessions.
Compensation
Not stated in the trial record.
Follow-up
Your symptoms will be monitored from when you are admitted to the hospital until three months after you are discharged.

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NCT07540585

MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

Not Yet Recruiting
Not specifiedAges 18+Observational
Indiana University
~50 participants
Updated 2026-04-22 on ClinicalTrials.gov
What's tested:Collaborative Mental Health Care Program (CMHCP)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in depressive symptoms measured by the Edinburgh Postnatal Depression Scale (EPDS)
Measured over From baseline (hospital admission) to 3 months post-discharge
+7 more outcomes measured
Anxiety Disorders
Stress Disorders, Post-Traumatic
Pregnancy, High Risk
Depressive Disorder, Major
Pregnancy Complications
ADHD - Attention Deficit Disorder With Hyperactivity
1 sites across 1 states
Indiana1
  • Tiffany R Williams, PhD · PRINCIPAL_INVESTIGATOR · Indiana University

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Eligibility criteria

Inclusion

18 years old or older
Pregnant (or recently have given birth) at any gestational age
Must have experienced at least one adverse pregnancy outcome
Admitted for an extended inpatient stay
English speaking

Exclusion

Under 18 years old
Not currently pregnant or past one year postpartum
Not experienced at least one adverse pregnancy outcome
Not admitted for an extended inpatient stay at RMT
  • Change in depressive symptoms measured by the Edinburgh Postnatal Depression Scale (EPDS)From baseline (hospital admission) to 3 months post-discharge

    The Edinburgh Postnatal Depression Scale (EPDS) is a validated 10-item self-report questionnaire assessing depressive symptoms. Total scores range from 0 to 30, with higher scores indicating more severe depressive symptoms. The outcome is defined as the change in EPDS total score.

  • Change in anxiety symptoms measured by the Generalized Anxiety Disorder 7 (GAD-7)From baseline (hospital admission) to 3 months post-discharge

    The Generalized Anxiety Disorder 7 (GAD-7) is a validated 7-item self-report questionnaire assessing anxiety symptoms. Total scores range from 0 to 21, with higher scores indicating greater anxiety. The outcome is defined as the change in GAD-7 total score.

  • Change in posttraumatic stress symptoms measured by the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5)From baseline (hospital admission) to 3 months post-discharge

    The Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) is a validated 5-item yes/no self-report screening tool assessing posttraumatic stress symptoms. Higher scores indicate greater likelihood of clinically significant PTSD symptoms. The outcome is defined as the change in PC-PTSD-5 total score.

  • Feasibility of weekly symptom screening during hospitalizationDuring hospitalization (from admission to discharge)

    Feasibility will be assessed as the percentage of enrolled participants who complete at least one weekly symptom mini-screen during hospitalization. Weekly mini-screens include abbreviated versions of the EPDS, GAD-7, and PC-PTSD-5 administered via REDCap. A participant will be considered compliant if all items within a given mini-screen are completed.

  • Acceptability of psychotherapy sessions measured by the Session Rating Scale (SRS)During hospitalization (from admission to discharge)

    The Session Rating Scale (SRS) is a 4-item visual analogue scale (0-10 per item), with total scores ranging from 0 to 40. Higher scores indicate stronger therapeutic alliance and greater acceptability. The outcome is defined as the change in SRS total score.

  • Fidelity to psychotherapy protocol: percentage of scheduled sessions deliveredDuring hospitalization (from admission to discharge)

    Fidelity will be assessed as the percentage of scheduled psychotherapy sessions that are delivered according to the study protocol. Protocol-adherent sessions are defined as CBT- or DBT-informed psychotherapy sessions lasting 45-60 minutes and documented by clinicians. The numerator will be the number of sessions delivered per protocol, and the denominator will be the total number of scheduled sessions during hospitalization.

  • Acceptability of the MOCHA program measured by the Client Satisfaction Questionnaire (CSQ-8)3 months post-discharge

    The Client Satisfaction Questionnaire (CSQ-8) is an 8-item self-report measure assessing overall satisfaction with the MOCHA program. Total scores range from 8 to 32, with higher scores indicating greater satisfaction. The outcome is defined as the change in CSQ-8 total score.

  • Change in symptoms of Attention Deficit Hyperactivity Disorder as measured by Adult ADHD Self-Report ScaleFrom baseline (hospital admission) to 3 months post-discharge

    The Adult ADHD Self-Report Scale (ASRS) is a validated self-report questionnaire assessing symptoms of attention-deficit/hyperactivity disorder (ADHD) in adults. The scale includes items assessing inattentive and hyperactive-impulsive symptoms, with higher scores indicating greater ADHD symptom severity. The outcome is defined as the change in PMSS total score.