A Study of JADE101 for IgA Nephropathy

This study is testing a drug called JADE101 in people with IgA nephropathy (a kidney disease). JADE101 is given as a shot under the skin. The main goal is to see how safe JADE101 is and if people can tolerate it, by tracking any side effects for about 100 weeks. You might be able to join if you are between 18 and 60 years old, have biopsy-confirmed IgA nephropathy, and your eGFR (a measure of kidney function) is 30 mL/min/1.73 m2 or higher. You also need to be on stable doses of certain blood pressure medications (ACEi or ARB) for at least 12 weeks. The study is currently unclear about its recruitment status.

Study design
This is an open-label Phase 2 study, meaning both you and the study team will know you are receiving JADE101. It plans to include about 30 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your safety will be monitored from the first day of treatment through 100 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07541287

A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

Recruiting
PHASE2Ages 18–60InterventionalTreatment
Jade Biosciences, Inc.
~30 participants
Updated 2026-08-20 on ClinicalTrials.gov
What's tested:JADE101

At a glance

Recruiting sites
15 of 15 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of treatment-emergent adverse events (safety and tolerability)
Measured over Day 1 through 100 weeks
IgA Nephropathy
15 sites across 8 states
South Korea6
Colorado2
Florida2
California1
Texas1
New South Wales1
New Zealand1
Taiwan1
  • Li Li, MD · STUDY_DIRECTOR · Jade BioSciences

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  • Incidence of treatment-emergent adverse events (safety and tolerability)Day 1 through 100 weeks

    The proportion of participants who experience one or more adverse events that begin or worsen after the first dose of study drug