Spiritual Health Intervention (PATH) for Cancer Patients

This study is exploring a spiritual health intervention called Personal Archetypes Toward Healing (PATH) for cancer patients. Many people with cancer experience emotional and spiritual challenges, affecting their sense of connection, meaning, and purpose. The PATH intervention aims to help improve these feelings of distress. This study will look at whether it's practical to offer PATH workshops and if patients find them helpful. You may be able to join if you are an adult with a cancer diagnosis, are receiving treatment or surveillance at Fred Hutch Cancer Center, speak English, and are experiencing some religious or spiritual struggles.

Study design
This is an interventional study with a planned enrollment of 20 participants. It is testing the feasibility and acceptability of the PATH intervention.
What's involved
You would attend one individual PATH session, followed by five weekly group PATH workshops. You would also complete surveys and interviews.
Compensation
Not stated in the trial record.
Follow-up
After completing the intervention, participants will have follow-up appointments on days 42 and 84.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07545291

A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients

Not Yet Recruiting
NAAges 18+InterventionalSupportive care
Fred Hutchinson Cancer Center
~20 participants
Updated 2026-09-17 on ClinicalTrials.gov
What's tested:Spiritual TherapySurvey AdministrationInterview

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Accrual rates (feasibility) (Aim 1)
Measured over At time of enrollment
+4 more outcomes measured
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

NCT07545291

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washingtonstudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • RaeAnne Wiseman · PRINCIPAL_INVESTIGATOR · Fred Hutch/University of Washington Cancer Consortium

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Eligibility criteria

Inclusion

Age 18 years of age or older
English speaking
Able to provide informed consent
Current diagnosis of cancer at any stage, engaged in active treatment or surveillance at Fred Hutch Cancer Center
Scores of "Somewhat" or above on at least 1 item the Religious and Spiritual Struggles scale (RSS-5) (e.g., Somewhat = 3 on a 1-to-5 Likert scale)

Exclusion

Non-oncology Fred Hutch patients
  • Accrual rates (feasibility) (Aim 1)At time of enrollment

    Feasibility will be examined by conducting frequency and descriptive statistics for enrollment rates. The benchmark for feasibility is ≥ 50% of screened eligible patients enroll in the study. To test this, will perform a one-sample proportion test to examine if the proportion of participants meeting the benchmark for feasibility is significantly higher than 0.50. Feasibility process outcomes will be analyzed to determine whether the intervention is feasible for future dissemination and implementation efforts and recruitment of a full-scale randomized controlled trial.

  • Rates of intervention completion (feasibility) (Aim 1)Up to day 84

    Intervention completion metrics will include all 6 intervention sessions as well as both follow-up timepoints (days 42 and 84). Patients will be required to attend at least 70% of all sessions (5 of 6). Feasibility will be examined by conducting frequency and descriptive statistics for intervention completion. The benchmark for feasibility is ≥ 70% of enrolled patients completing the intervention. To test this, will perform a one-sample proportion test to examine if the proportion of participants meeting the benchmark for feasibility is significantly higher than 0.70. Feasibility process outcomes will be analyzed to determine whether the intervention is feasible for future dissemination and implementation efforts and recruitment of a full-scale randomized controlled trial.

  • Acceptability (Aim 1)Up to day 42

    Acceptability will be assessed by the Theoretical Framework of Acceptability (TFA) questionnaire and three additional quality improvement questions. To analyze intervention acceptability, scores on the TFA questionnaire will be calculated using the total mean score of seven TFA items. In this study, will use a cutoff of \>= 70% of patients agreeing (or rating as confident, liking, acceptable or 4 out of 5 or higher on the TFA) as being acceptable for use.

  • Satisfaction (Aim 1)Up to day 42

    Satisfaction will be assessed by using three items assessing overall satisfaction. Satisfaction thresholds will require an average or mean of 7 out of 10 on each of the three items.

  • Change in spiritual, religious, and existential (SRE) distress as measured by the Religious and Spiritual Struggles Scale-5 (RSS-5) (Aim 2)At baseline and 1- and 6-week follow-up (days 42 and 84)

    Spiritual, religious, and existential (SRE) distress will be measured using the Religious and Spiritual Struggles Scale-5 (RSS-5), a valid and reliable 5-item Likert-type self-report measure of spiritual struggle. Each item is rated on a 5-point scale ranging from 1 ("not at all") to 5 ("a great deal"). Item scores are summed or averaged to create an overall SRE distress score. Total mean score ranges from 1 to 5, with higher scores indicating greater levels of SRE distress. Change in SRE distress will be assessed at baseline and at 1- and 6-week follow-up.