CARRII Native Intervention Optimization Trial for Fetal Alcohol Spectrum Disorders

This study is testing different combinations of components with CARRII Native Cores, an online program designed to help Native American/American Indian/Alaska Native women reduce their risk of alcohol-exposed pregnancies (AEP). The goal is to find the most effective and affordable version of this program. You may be able to join if you are a Native American/American Indian/Alaska Native woman between 18 and 44 years old, are not surgically sterile, have consumed alcohol at risky levels, and have had unprotected sex with a man in the last 90 days. You also need daily internet access on a mobile device. The study will measure the rate of AEP risk after 3 months to see how well the interventions work. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 512 participants in a 3-month factorial experiment. This design helps researchers test multiple intervention components at once.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 3 months to measure the rate of Alcohol Exposed Pregnancy (AEP) Risk.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07547696

CARRII Native Intervention Optimization Trial

Recruiting
NAAges 18–44Interventional
University of Virginia
~512 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:CARRII Native Cores

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of Alcohol Exposed Pregnancy (AEP) Risk
Measured over 3 months
Fetal Alcohol Spectrum Disorders
Pregnancy
Alcohol-Related Disorders
Drinking, Alcohol
Contraception Behavior
Alcohol Exposed Pregnancy
Sexual Behavior
1 sites across 1 states
Virginia1
  • Karen S Ingersoll, PhD · PRINCIPAL_INVESTIGATOR · University of Virginia
  • Lee M Ritterband, PhD · PRINCIPAL_INVESTIGATOR · University of Virginia

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Native American/American Indian/Alaska Native,
who are not surgically sterile,
who report alcohol consumption at risk levels and risk for pregnancy in the past 90 days due to having sex with a man with inconsistent, ineffective, or no contraception.
Participants must have access to the Internet via a mobile device they can access daily

Exclusion

cognitive disorders including mental retardation, dementia, or psychotic disorders that could impair ability to understand the intervention material or give informed consent.
  • Rate of Alcohol Exposed Pregnancy (AEP) Risk3 months

    The primary outcome will be risk of alcohol-exposed pregnancy in the past month, at the 3 Month (3M) follow-up via daily diary reporting of alcohol consumption, intercourse and contraception use. AEP risk is defined as 1) had vaginal sex with a male during the past 4 weeks, 2) drank alcohol at risk levels during the past 30 days (For women, risky alcohol use is drinking more than 7 standard drinks per week, or more than 3 standard drinks per occasion, or both), 3) past month intermittent or no contraception, and 4) not being sterile and not having a partner (or partners) known to be sterile.