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Lidocaine Infusion for Pain Control in Pediatric Arm Fracture Surgery

This study is looking at whether giving lidocaine (a numbing medicine) through an IV during surgery for arm fractures in children can help reduce the amount of pain medication (opioids) they need. Children aged 3 to 18 years old who are having surgery for an upper arm fracture at Nemours Children's Hospital - Delaware Valley might be able to join. Half of the participants will receive lidocaine during surgery, and the other half will receive a placebo (inactive substance). The main goal is to see if the lidocaine group uses less opioid pain medicine within 60 minutes after waking up from surgery. The study plans to enroll 90 children.

Study design
This is a randomized, double-blind study, meaning participants are randomly assigned to receive either lidocaine or a placebo, and neither you nor your doctors will know which you are receiving. The study plans to enroll 90 participants.
What's involved
You would receive either lidocaine or a placebo during your surgery. Your pain and opioid use will be measured during and after surgery.
Compensation
Not stated in the trial record.
Follow-up
Your opioid consumption will be measured up to 60 minutes after arriving in the post-anesthesia care unit (PACU).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07552766

A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements

Recruiting
PHASE4Ages 3–18InterventionalTreatment
Nemours Children's Clinic
~90 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:Lidocaine InfusionStandard of Care (SOC)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Total perioperative opioid consumption
Measured over 60 minutes after patient arrival to post-anesthesia care unit (PACU)

Conditions

Fracture Arm
Fracture Closed of Lower End of Forearm, Unspecified
Fracture Elbow
Fracture Fixation
Fracture Fixation, Internal
Fracture Forearm
Fracture Distal Radius

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Arm Fracture

NCT07552766

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Nemours Children's Hospital

    Wilmington, Delawarestudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Angela Snow, MD
[email protected]
302-824-1792
Email the study team

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Eligibility criteria

Inclusion

Patients aged 3-18 years
Patients \> 10 kg
Patients who present to Nemours Children's Hospital - Delaware Valley (NCH-DE) for surgical fixation of upper extremity fractures from distal humerus to distal radius

Exclusion

Children \< 3 years or \> 18 years
Patients with allergy to local anesthetics
Patients who are eligible for an receive a peripheral nerve block
Patients with multi-trauma or open fractures
Patients with previous history of seizure disorder
Patients with conduction abnormalities or cardiac arrhythmia requiring chronic treatment
Patients on strong CYP450 inhibitors (fluvoxamine, erythromycin, ciprofloxacin, rifampin, allopurinol, ketoconazole, itraconazole)
Patients with chronic kidney or liver dysfunction
Patients with planned use of continuous infusion pain medications (opioids, ketamine, alpha-2- agonists)
Patients with positive pregnancy test prior to surgery or nursing mothers
Patients who parents decline enrollment

What this trial measures

  • Total perioperative opioid consumption60 minutes after patient arrival to post-anesthesia care unit (PACU)

    Determine the effect of IVLI on intraoperative and postoperative opioid consumption in pediatric patients undergoing orthopedic surgery for long bone fractures of the upper extremity