Survey on Nicotine Labels for E-cigarettes

This study is looking at new ways to label e-cigarettes so people better understand how much nicotine they contain. Researchers want to create and test two new types of labels: one for nicotine concentration (how much nicotine is in the product) and another for nicotine flux (how much nicotine is released when you use it). The goal is to find out if these updated labels, called Updated Labeling, help both young people (ages 14-20) and adults (ages 21 and older) understand nicotine strength better than current labels. The study will survey 2500 participants in the United States, including those who have never used tobacco and those who use e-cigarettes. Success will be measured by how people perceive nicotine strength after seeing the new labels, specifically 20 minutes after viewing them.

Study design
This is an interventional study that plans to enroll 2500 participants. It is not specified if the study is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, perceived nicotine strength, is measured at 20 minutes.

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NCT07553585

Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes

Not Yet Recruiting
NAAges 14+Interventional
Yale University
~2,500 participants
Updated 2026-08-17 on ClinicalTrials.gov
What's tested:Updated Labeling

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Perceived Nicotine Strength
Measured over 20 minutes
Nicotine Labeling for E-cigarettes
1 sites across 1 states
Connecticut1

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Eligibility criteria

Inclusion

Youth\* (14-20 years) or an adults (21 years and older)
The legal age for purchasing tobacco in the U.S. is 21 years. Therefore, ages for youth and adults were split at the legal age for purchase.
Resides in the United States
Reports no history of tobacco product use (25% of the youth and adult samples, respectively) or past-month use of e-cigarettes (but not cigarettes; 25%), cigarettes (but not e-cigarettes; 25%), or both e-cigarettes and cigarettes (25%).

Exclusion

Children under 14 years
  • Perceived Nicotine Strength20 minutes

    To assess the impact of the new labels on understanding of the nicotine strength of e-cigarettes, perceived nicotine strength will be assessed. Participants will see each label at four nicotine strengths. After viewing each label/strength combination, participants will report on perceived strength. A correct response will be one that corresponds to what the label depicts. For instance, a response of "high nicotine" would be correct if a flux label visually depicts nicotine emissions in the high range. The total number of correct strength ratings for each label type (i.e., the market mg/mL label, the new nicotine concentration labels, the new flux labels) will be calculated and compared to one another to determine which label is most informative. The primary hypothesis is that the new nicotine concentration and flux label(s) will outperform mg/mL market labeling in accurately conveying liquid nicotine strength.