Oral Health Study for Head and Neck Cancer Patients After Radiation

This study is looking at how well fluoride varnish treatment works to improve oral health for head and neck cancer patients who have had radiation and have limited access to dental care. It's a pilot study, meaning it's a small-scale test to see if this approach is practical. You might be eligible if you are over 18, have head and neck cancer, have received immunotherapy or enhanced chemotherapy, and have certain insurance types (uninsured, underinsured, or full coverage). The study will look at how easy it is to provide fluoride varnish during regular cancer check-ups and how it affects your dental health. Researchers will also gather information about your experiences with dental care and any challenges you face.

Study design
This is an interventional pilot study with a planned enrollment of 43 participants. It is not specified if it is randomized or blinded.
What's involved
You would complete surveys, provide saliva samples, have intra-oral photographs taken, and receive fluoride varnish treatment every 3 months for a year. You and your caregivers would also participate in interviews.
Compensation
Not stated in the trial record.
Follow-up
The feasibility of the intervention will be measured for up to one year. Interviews will be conducted for up to one day.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07556367

Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients

Active, Not Recruiting
NAAges 18+InterventionalTreatment
University of California, San Francisco
~43 participants
Updated 2026-06-01 on ClinicalTrials.gov
What's tested:SurveysSaliva CollectionIntra-oral photographsFluoride Varnish TreatmentInterview (Participant)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Mean score of Feasibility of Intervention Measure (FIM)
Measured over Up to 1 year
+1 more outcome measured
Head and Neck Cancer
Head and Neck Carcinoma
Head and Neck Neoplasms
1 sites across 1 states
California1
  • Mary J Xu, MD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Mean score of Feasibility of Intervention Measure (FIM)Up to 1 year

    The Feasibility of Intervention Measure (FIM) is a 4-item implementation measure that assesses participants or providers' perceived feasibility of the intervention. Responses are rated on a 5-point Likert scale ranging from 1 (Completely Disagree) to 5 (Completely Agree). The survey is administered at baseline and at each surveillance visit.

  • InterviewUp to one day

    Interview will be conducted with participants and providers using guided questions. Responses will be analyzed to assess the feasibility and potential for expanding the fluoride varnish program.