100-Year Human Aging Study

The 100-Year Human Aging Study is an observational study looking at how different health measurements predict how long people live and their overall health as they age. This study involves a "Comprehensive Multi-System Clinical Screening" which includes tests like exercise testing, body composition scans (DEXA), heart tests (echocardiography, electrocardiography), breathing tests (spirometry), and memory tests. Researchers want to see if these measurements, taken over time, can help predict when someone might pass away or develop serious diseases and disabilities. You can join if you are 18 years or older and are willing to have regular health screenings and be followed for a long time. The study aims to enroll one million participants.

Study design
This is an observational study, meaning researchers will watch and collect information without giving specific treatments. It plans to enroll one million participants.
What's involved
You would undergo a comprehensive multi-system clinical screening and participate in longitudinal follow-up until death. This involves various tests like exercise testing, DEXA scans, and heart and breathing tests.
Compensation
Not stated in the trial record.
Follow-up
You will be followed from enrollment until death, with assessments periodically, for up to 100 years.

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NCT07563777

100-Year Human Aging Study

Recruiting
Not specifiedAges 18+Observational
Longevity Metrics, Inc.
~1,000,000 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:Comprehensive Multi-System Clinical Screening

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
All-Cause Mortality
Measured over From enrollment until death, assessed periodically, up to 100 years
+1 more outcome measured
Aging
Aging Well
All-Cause Mortality
Mortality
Metabolic Syndrome
Cardiovascular Diseases
Cognitive Dysfunction
Musculoskeletal Diseases
Neoplasms
Frailty
Activities of Daily Living
Health-Related Quality of Life
Disability Physical
Neuro-Degenerative Disease
Dementia
1 sites across 1 states
Colorado1
  • William E Brandenburg, MD · PRINCIPAL_INVESTIGATOR · Longevity Metrics, Inc.

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Eligibility criteria

Inclusion

Age 18 years or older
Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative
Willing to participate in longitudinal follow-up

Exclusion

Age under 18 years
  • All-Cause MortalityFrom enrollment until death, assessed periodically, up to 100 years

    Vital status ascertained through longitudinal follow-up contact, mortality record linkage, and health data network linkage using probabilistic matching on name, date of birth, and address history.

  • Cause-Specific MortalityFrom enrollment until death, assessed periodically, up to 100 years

    Cause of death ascertained via death certificate and mortality record linkage.