Reducing Opioid Prescribing After Surgery in Southeastern North Carolina

This study aims to improve how opioids are prescribed after surgery in hospitals across Southeastern North Carolina. Researchers are comparing current prescribing practices (Usual Care) with a new approach called the Opioid Stewardship Intervention. This intervention includes tools, educational sessions for doctors and nurses, and reports on prescribing patterns. The study wants to see if this new approach reduces the amount of opioids prescribed after surgery and if it's practical and well-received by hospital staff. You could be eligible to participate if you are a surgeon, pharmacist, nurse, or other healthcare provider working at one of the participating hospitals, or a patient representative who has been prescribed opioids after a qualifying general surgery procedure. The study is currently unclear on its status and plans to enroll 40 participants.

Study design
This study is a stepped-wedge cluster randomized trial involving 40 participants. It compares existing opioid prescribing practices with a new Opioid Stewardship Intervention.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The intervention's acceptability and feasibility will be measured from enrollment through 6 months after the 10-week intervention period.

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NCT07566182

Reducing Post-Operative Opioid Prescribing in Southeastern North Carolina

Not Yet Recruiting
NAAges 18+InterventionalHealth services
University of North Carolina, Chapel Hill
~40 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:Usual CareOpioid Stewardship Intervention

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Acceptability of the Intervention Assessed by Semi-Structured Interviews (Change Team Members)
Measured over From enrollment through 6 months after completion of the 10-week intervention period
+7 more outcomes measured
Opioid Prescribing
2 sites across 1 states
North Carolina2
  • Jessica Schumacher, PhD · PRINCIPAL_INVESTIGATOR · University of North Carolina, Chapel Hill

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  • Acceptability of the Intervention Assessed by Semi-Structured Interviews (Change Team Members)From enrollment through 6 months after completion of the 10-week intervention period

    Acceptability will be assessed qualitatively using themes derived from semi-structured interviews conducted with change team members. Interviews will explore perceptions of the intervention and its fit within the hospital context. Themes identified after the 10-week implementation period will be compared with themes identified prior to implementation.

  • Proportion of training and learning sessions attended (Feasibility Measure 1)From enrollment through 6 months after completion of the 10-week intervention period

    Proportion of training and learning sessions attended by change team members

  • percentage of change team member providers that completed pre- and post- assessments (Feasibility Measure 2)From enrollment through 6 months after completion of the 10-week intervention period

    percentage of change team member providers that completed pre- and post- assessments

  • change team's ability to start the trial as randomized (Feasibility Measure 3)From enrollment through 6 months after completion of the 10-week intervention period

    change team's ability to start the trial as randomized (yes/no)

  • proportion of intervention components implemented (Feasibility Measure 4)From enrollment through 6 months after completion of the 10-week intervention period

    proportion of intervention components implemented using themes gathered from semi-structured interviews (intervention fidelity)

  • Change in Organizational Readiness to Change (ORIC) Measure (Effectiveness Measure 1- survey)From enrollment through 6 months after completion of the 10-week intervention period)

    Change in ORIC score from pre- to post intervention. Change team members will complete the survey before the intervention start phase and after intervention completion.

  • Audit and feedback effectiveness as assessed by learning sessions and semi structured interviews (Effectiveness Measure 2)Intervention Period

    Audit and feedback effectiveness is defined as the extent change team members feel ownership and agreement, can make sense of the information provided, are motivated by the social influence that reviewing their performance shows (e.g., comparing their performance to other hospitals), and accept accountability for the proposed changes.

  • Change in Milligram equivalents (MME) of the first post-operative fill pre- and post-intervention using administrative claims data (Effectiveness Measure 3).Comparing pre (6 months before enrollment) and 6 month period starting at the end of the 10-week intervention period.

    Change in Milligram equivalents (MME) of the first opioid prescription filled (outpatient) by patients -3 days before admission for their qualifying procedure through 7 days post-discharge during the pre- and post-intervention time periods.