Avocado for Inflammation in Overweight and Obese Adults

This study is looking at how replacing refined carbohydrates (like added sugars) with avocado affects inflammation in adults who are overweight or obese. You might be able to join if you are between 21 and 74 years old, have a BMI (Body Mass Index) between 25 and 39.9, and have elevated hs-CRP (a marker of inflammation) and central adiposity (extra fat around your waist). The researchers want to see if eating avocado instead of refined carbs can improve your inflammation markers. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 38 participants. It compares two 4-week diet conditions: one with avocado and one with control foods.
What's involved
You would complete two 4-week diet periods, separated by a 2-week break. This involves a total of 7 clinic visits over the study duration.
Compensation
Not stated in the trial record.
Follow-up
Inflammatory biomarkers will be measured at the end of each 28-day diet condition, comparing them to your baseline measurements.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07566325

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

Recruiting
NAAges 21–74Interventional
Midwest Center for Metabolic and Cardiovascular Research
~38 participants
Updated 2026-08-27 on ClinicalTrials.gov
What's tested:AvocadoControl

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Composite measure of inflammatory biomarkers
Measured over Change from baseline (day 0) to end of each condition (day 28)
Overweight (BMI > 25)
Obesity (BMI>30)
Hs-CRP
2 sites across 2 states
Illinois1
Nevada1

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  • Composite measure of inflammatory biomarkersChange from baseline (day 0) to end of each condition (day 28)

    Change from baseline for a composite measure of inflammatory biomarkers including high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), interleukin-1 beta (IL-1β), interleukin-10 (IL-10), and tumor Necrosis Factor-alpha (TNF-α).