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Brain Activity in Youth with ADHD and OCD

This study aims to understand how the brain controls thinking and behavior in young people aged 10 to 17. Researchers are looking at differences in brain activity, specifically theta frequency oscillations, between healthy youth, those with Attention Deficit Hyperactivity Disorder (ADHD), and those with Obsessive Compulsive Disorder (OCD). The goal is to learn more about these conditions and how brain activity might be linked to them. This information could help plan future studies that use brain stimulation to improve cognitive control in youth with ADHD and OCD. The study will measure how well participants stay in the study, report any side effects, and the quality of brain scan data.

Study design
This is an observational study planning to enroll 110 participants. It will compare brain activity in healthy youth, youth with ADHD, and youth with OCD.
What's involved
You would have 3 to 10 clinic visits over up to one year, with each visit lasting 2 to 3 hours. At least three visits are required, including one where you complete a computer task.
Compensation
Not stated in the trial record.
Follow-up
Adverse events and participant retention will be measured at each visit, and data quality will be assessed at the time of assessment.

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NCT07566468

Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)

Not Yet Recruiting
Not specifiedAges 10–17Observational
National Institute of Mental Health (NIMH)
~110 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Participant Retention for all visits of the study and task performance.
Measured over At each visit
+3 more outcomes measured

Conditions

ADHD
Obsessive Compulsive Disorder (OCD)
Healthy Volunteer

Explore related trials

Attention Deficit Hyperactivity DisorderHealthy VolunteerObsessive Compulsive Disorder

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Lindsay M Oberman, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Mental Health (NIMH)

Who to contact

Lindsay M Oberman, Ph.D.
[email protected]
(301) 435-7962
Email the study team

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What this trial measures

  • Participant Retention for all visits of the study and task performance.At each visit

    Withdrawal rates and Accuracy rates on task.

  • Adverse Events reported related to study proceduresAt each visit

    Patient Reported Negative Side Effects

  • Percentage of EEG and fMRI data deemed to be of sufficient quality for analysis (e.g. without artifact or excessive motion).At time of assessment

    Amount of analyzable data

  • Structural cortical region source localized from a combination of the EEG (and MEG in a subset of patients) and fMRI dataAt time of assessment

    Location of brain activation