Observational Study on Gut-Brain Connection in Parkinson's Disease
This study, called GBPDC, is looking into how the connection between your gut and brain (the gut-brain axis) might be involved in Parkinson's disease (PD). Researchers want to understand how this connection changes in people with PD, those at risk for PD, and those without the disease. They will compare different groups of people based on their PD status and severity. The study aims to collect information and samples over 24 months to better understand PD and potentially find new ways to diagnose or treat it. You might be able to join if you are between 21 and 80 years old and have a clinical diagnosis of PD, or if you are at risk for PD, or do not have PD.
- Study design
- This is an observational study aiming to enroll 250 participants. It will compare different groups of people based on their Parkinson's disease status.
- What's involved
- You would participate in scheduled visits, laboratory tests, and other study procedures. The observation period for primary endpoints is up to 24 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be observed for up to 24 months to assess GI influences on PD and co-associations components of the gut-brain axis.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
GBPDC: Gut-Brain in PD Consortium Master Protocol
At a glance
Conditions
Where it's being run
7 sites across 6 statesStudy leadership
- Lisa Wruck · PRINCIPAL_INVESTIGATOR · Duke Clinical Research Institute
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- GI influences on PDenrollment to end of observation at 24 months
Trait and State cross-sectional evaluation of GI influences on PD
- Co-associations components of the GBAenrollment to end of observation at 24 months
Cross-sectional co-associations components of the GBA