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Optimizing Text Messages for Colorectal Cancer Screening

This study aims to improve colorectal cancer (CRC) screening rates in community health centers by optimizing text message programs. Researchers will first gather input from clinic staff and patients to design effective text messages. Then, they will test different versions of text messages, including personalized messages, messages addressing emotional concerns about screening, and messages using 'gain-framed' language (focusing on benefits). The goal is to encourage more patients, aged 45-75, to complete at-home stool-based CRC screening tests and ensure they receive follow-up care if needed. The study will measure how often patients engage with the text messages and how many complete their screening within three months.

Study design
This interventional study plans to enroll 7220 participants. It will involve focus groups and interviews to design text messages, followed by a factorial experiment testing different message versions.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Text message engagement will be measured 14 days after a reminder message, and stool-based CRC screening completion will be measured 3 months after a reminder message.

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NCT07569250

Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization

Not Yet Recruiting
NAAges 45–75InterventionalHealth services
University of Colorado, Denver
~7,220 participants
Updated 2026-07-10 on ClinicalTrials.gov
What's tested:Personalized Text MessageScreening Concerns Text MessageMessage Framing Text MessageAutonomy Support OutreachImpediments Support OutreachLive Support Outreach

At a glance

Recruiting sites
0 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Text message engagement
Measured over 14 days after reminder message delivery
+1 more outcome measured

Conditions

Colorectal Cancer

Explore related trials

Colorectal Carcinoma

Where it's being run

4 sites across 2 states
Massachusetts3
Texas1

Study leadership

  • Gina Kruse, MD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

Who to contact

Yamila Sierra
[email protected]
303-724-4811
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults 45-75 years old
Receive care in partner CHCs
Are of average risk for colorectal cancer
Received a stool-based testing order at their CHC
Have a mobile phone and can receive text messages (Aim 1 quantitative cohort only)
Fluent in English, Spanish, or another predominant language to be identified by the PI (applicable to patients focus groups cohort only)
Adult employees of participating CHCs
Job responsibilities include activities related to CRC screening

Exclusion

Personal or family history of CRC or colorectal polyps
History of inflammatory bowel disease
Heritable conditions that put them at above average risk for colorectal cancer (e.g., familial adenomatous polyposis)
None

What this trial measures

  • Text message engagement14 days after reminder message delivery

    Proportion of message recipients who interact with CRC screening reminder messages by reply

  • Stool-based CRC screening completion3 months after reminder message delivery

    Proportion of message recipients with stool-based CRC screening tests resulted in electronic health record