A Study Of Synthetic THC And Sleep
{ "A Study of Dronabinol and Sleep Apnea", "This study is looking at whether a synthetic form of THC called Dronabinol can help people with Obstructive Sleep Apnea (OSA) use their CPAP machine more consistently and improve their sleep. Researchers also want to see if Dronabinol, when taken before sleep, can help regulate blood pressure. You might be able to join if you are 21-70 years old, male or female, and have moderate to severe OSA. The study will measure how often you use your CPAP, your apnea-hypopnea index (a measure of breathing pauses during sleep), and your physical activity. The study plans to enroll 72 participants, but its current status is unclear.", "design": "This is an interventional study planning to enroll 72 participants. Participants will receive either Dronabinol or a placebo daily for 6 weeks.", "commitments": "You would take either Dronabinol or a placebo daily for 6 weeks. Your breathing pauses during sleep will be measured at Day 15, Day 29, and Day 42, and your physical activity at the beginning and end of the study.", "compensation": "Not stated in the trial record.", "follow_up": "The study measures outcomes up to Day 42, which is the end of the 6-week treatment period.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study Of Synthetic THC And Sleep
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Virend Somers, M.D., Ph.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Number of times subjects complete CPAP therapyBaseline
CPAP therapy is defined as using the therapeutic device for ≥ 4 hours per night
- Apnea-hypopnea index (AHI)Day 15, Day 29, and Day 42
Apnea-hypopnea index (AHI) an index used to describe the number of apneas experienced during sleep. It is calculated by (Number of hours of sleep/Number of Apneas or hypopneas). This value will then be graded on a scale from Normal (\<5) to Severe (\>30).
- International Physical Activity QuestionnaireBaseline and Day 42
International Physical Activity Questionnaire is a 0-10 visual analog scale to assess self-reported sleep quality